Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HRH3 | Q9Y5N1 | 1/20 | 0.59 |
| ▸ | HSD17B10 | Q99714 | 5/20 | 0.58 |
| ▸ | MAPT | P10636 | 3/20 | 0.58 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.58 |
| ▸ | CYP2C9 | P11712 | 2/20 | 0.58 |
| ▸ | CYP2C19 | P33261 | 2/20 | 0.58 |
| ▸ | LMNA | P02545 | 5/20 | 0.58 |
| ▸ | ESR1 | P03372 | 5/20 | 0.54 |
| ▸ | SMN1; SMN2 | Q16637 | 3/20 | 0.54 |
| ▸ | PGR | P06401 | 2/20 | 0.54 |
| ▸ | AR | P10275 | 2/20 | 0.54 |
| ▸ | SLC6A3 | Q01959 | 2/20 | 0.54 |
| ▸ | ADORA3 | P0DMS8 | 2/20 | 0.54 |
| ▸ | ATM | Q13315 | 2/20 | 0.54 |
| ▸ | ABCC1 | P33527 | 1/20 | 0.54 |
| ▸ | ABCC4 | O15439 | 1/20 | 0.54 |
| ▸ | CHRM1 | P11229 | 1/20 | 0.54 |
| ▸ | TBXA2R | P21731 | 1/20 | 0.54 |
| ▸ | ADRA1A | P35348 | 1/20 | 0.54 |
| ▸ | OPRM1 | P35372 | 1/20 | 0.54 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL5166260 | 0.90 | LMNA (0.71) | HRH3HSD17B10MAPTALDH1A1CYP2C9 | |
| SCHEMBL11860032 | 0.90 | LMNA (0.71) | HRH3HSD17B10MAPTALDH1A1CYP2C9 | |
| SCHEMBL11672711 | 0.90 | LMNA (0.71) | HRH3HSD17B10MAPTALDH1A1CYP2C9 | |
| SCHEMBL1681785 | 0.86 | HSD17B10 (0.78) | HSD17B10MAPTALDH1A1CYP2C9CYP2C19 | |
| SCHEMBL18687584 | 0.86 | HSD17B10 (0.78) | HSD17B10MAPTALDH1A1CYP2C9CYP2C19 | |
| SCHEMBL5164676 | 0.85 | ESR2 (0.70) | HSD17B10MAPTALDH1A1CYP2C9CYP2C19 | |
| SCHEMBL11574519 | 0.85 | ESR2 (0.70) | HSD17B10MAPTALDH1A1CYP2C9CYP2C19 | |
| SCHEMBL11861850 | 0.82 | LMNA (0.69) | HSD17B10MAPTALDH1A1CYP2C9CYP2C19 | |
| SCHEMBL16937721 | 0.82 | LMNA (0.71) | HSD17B10MAPTALDH1A1CYP2C9CYP2C19 | |
| SCHEMBL11854984 | 0.81 | HRH3 (0.53) | HRH3HSD17B10MAPTALDH1A1CYP2C9 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-3959322-A | Synthesis of 13-alkyl-gon-4-ones | Smith, Herchel (US) | 1976-05-25 | — | — | US | disclosed |