Predicted protein targets (top 13)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | AR | P10275 | 13/20 | 0.50 |
| ▸ | TTR | P02766 | 2/20 | 0.49 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.47 |
| ▸ | USP2 | O75604 | 1/20 | 0.47 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.47 |
| ▸ | PGR | P06401 | 1/20 | 0.45 |
| ▸ | IMPDH2 | P12268 | 1/20 | 0.43 |
| ▸ | IMPDH1 | P20839 | 1/20 | 0.43 |
| ▸ | FNTA | P49354 | 1/20 | 0.43 |
| ▸ | FNTB | P49356 | 1/20 | 0.43 |
| ▸ | PGGT1B | P53609 | 1/20 | 0.43 |
| ▸ | KCNJ1 | P48048 | 1/20 | 0.43 |
| ▸ | KCNH2 | Q12809 | 1/20 | 0.43 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL2020304 | 0.89 | ALDH1A1 (0.56) | ARTTRKDM4EUSP2ALDH1A1 | |
| SCHEMBL12188729 | 0.84 | AR (0.55) | ARKDM4EUSP2ALDH1A1PGR | |
| SCHEMBL2787679 | 0.82 | AR (0.50) | ARKDM4EUSP2ALDH1A1PGR | |
| SCHEMBL25735784 | 0.82 | AR (0.50) | ARKDM4EUSP2ALDH1A1PGR | |
| SCHEMBL6483428 | 0.82 | KDM4E (0.51) | ARKDM4EUSP2ALDH1A1PGR | |
| SCHEMBL25077588 | 0.82 | AR (0.50) | ARKDM4EUSP2ALDH1A1PGR | |
| SCHEMBL2786569 | 0.82 | AR (0.58) | ARKDM4EUSP2ALDH1A1PGR | |
| SCHEMBL7669160 | 0.82 | AR (0.50) | ARKDM4EUSP2ALDH1A1PGR | |
| SCHEMBL14405827 | 0.81 | AR (0.56) | ARKDM4EUSP2ALDH1A1PGR | |
| SCHEMBL13547923 | 0.79 | AR (0.51) | ARKDM4EUSP2ALDH1A1PGR |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2017024996-A1 | HYDROXY AMIDINE DERIVATIVE, PREPARATION METHOD AND USE IN MEDICINE THEREOF | 江苏恒瑞医药股份有限公司 | 2017-02-16 | — | — | WO | disclosed |
| US-3956363-A | Substituted indenyl acetic acids | MERCK & CO., INC. (US) | 1976-05-11 | — | — | US | disclosed |