Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 4/20 | 0.56 |
| ▸ | KDM4E | B2RXH2 | 5/20 | 0.44 |
| ▸ | HSD17B10 | Q99714 | 3/20 | 0.44 |
| ▸ | NPC1 | O15118 | 2/20 | 0.44 |
| ▸ | HCRTR1 | O43613 | 1/20 | 0.44 |
| ▸ | USP2 | O75604 | 1/20 | 0.44 |
| ▸ | TP53 | P04637 | 1/20 | 0.44 |
| ▸ | MAPT | P10636 | 1/20 | 0.44 |
| ▸ | TSHR | P16473 | 1/20 | 0.44 |
| ▸ | CASP1 | P29466 | 1/20 | 0.44 |
| ▸ | CASP7 | P55210 | 1/20 | 0.44 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.44 |
| ▸ | MAPK1 | P28482 | 3/20 | 0.43 |
| ▸ | SLC6A4 | P31645 | 2/20 | 0.43 |
| ▸ | HTT | P42858 | 2/20 | 0.43 |
| ▸ | LMNA | P02545 | 2/20 | 0.43 |
| ▸ | HPGD | P15428 | 2/20 | 0.43 |
| ▸ | SLC6A2 | P23975 | 1/20 | 0.43 |
| ▸ | HRH1 | P35367 | 1/20 | 0.43 |
| ▸ | PDE5A | O76074 | 1/20 | 0.42 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL12930508 | 0.78 | HTT (0.57) | ALDH1A1KDM4EHSD17B10NPC1TP53 | |
| SCHEMBL11835403 | 0.74 | ALDH1A1 (0.57) | ALDH1A1KDM4EHSD17B10NPC1HCRTR1 | |
| SCHEMBL7668668 | 0.74 | ALDH1A1 (0.57) | ALDH1A1KDM4EHSD17B10NPC1HCRTR1 | |
| SCHEMBL116890 | 0.73 | ALDH1A1 (1.00) | ALDH1A1KDM4EHSD17B10MAPTMAPK1 | |
| SCHEMBL7290888 | 0.70 | ALDH1A1 (0.61) | ALDH1A1KDM4EHSD17B10NPC1HCRTR1 | |
| SCHEMBL151563 | 0.68 | ALDH1A1 (0.75) | ALDH1A1KDM4EHSD17B10NPC1HCRTR1 | |
| SCHEMBL29360167 | 0.68 | ALDH1A1 (0.75) | ALDH1A1KDM4EHSD17B10NPC1HCRTR1 | |
| SCHEMBL29963695 | 0.68 | ALDH1A1 (0.75) | ALDH1A1KDM4EHSD17B10NPC1HCRTR1 | |
| SCHEMBL11865750 | 0.68 | P2RX4 (0.49) | ALDH1A1KDM4EUSP2MAPTTSHR | |
| SCHEMBL10022925 | 0.67 | ALDH1A1 (0.85) | ALDH1A1KDM4EHSD17B10MAPTMAPK1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-3936453-A | 1-Substituted-2-disubstituted aminoquin azolin-4(1h)-ones | SANDOZ, INC. (US) | 1976-02-03 | — | — | US | disclosed |