Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HDAC3 | O15379 | 3/20 | 0.57 |
| ▸ | HDAC4 | P56524 | 3/20 | 0.57 |
| ▸ | HDAC1 | Q13547 | 3/20 | 0.57 |
| ▸ | HDAC2 | Q92769 | 3/20 | 0.57 |
| ▸ | HDAC8 | Q9BY41 | 3/20 | 0.57 |
| ▸ | HDAC6 | Q9UBN7 | 3/20 | 0.57 |
| ▸ | HDAC7 | Q8WUI4 | 2/20 | 0.57 |
| ▸ | HDAC10 | Q969S8 | 2/20 | 0.57 |
| ▸ | HDAC11 | Q96DB2 | 2/20 | 0.57 |
| ▸ | HDAC9 | Q9UKV0 | 2/20 | 0.57 |
| ▸ | HDAC5 | Q9UQL6 | 2/20 | 0.57 |
| ▸ | MAOB | P27338 | 7/20 | 0.53 |
| ▸ | CA12 | O43570 | 1/20 | 0.49 |
| ▸ | CA1 | P00915 | 1/20 | 0.49 |
| ▸ | CA2 | P00918 | 1/20 | 0.49 |
| ▸ | TYR | P14679 | 1/20 | 0.49 |
| ▸ | CA7 | P43166 | 1/20 | 0.49 |
| ▸ | CA9 | Q16790 | 1/20 | 0.49 |
| ▸ | CA14 | Q9ULX7 | 1/20 | 0.49 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.47 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL523184 | 0.95 | HDAC3 (0.62) | HDAC3HDAC4HDAC1HDAC2HDAC8 | |
| SCHEMBL523185 | 0.95 | HDAC3 (0.62) | HDAC3HDAC4HDAC1HDAC2HDAC8 | |
| SCHEMBL14080887 | 0.95 | HDAC3 (0.62) | HDAC3HDAC4HDAC1HDAC2HDAC8 | |
| SCHEMBL15164766 | 0.93 | HDAC3 (0.61) | HDAC3HDAC4HDAC1HDAC2HDAC8 | |
| Cyclopropane SCHEMBL11845914 | 0.91 | HDAC6 (0.52) | HDAC3HDAC4HDAC1HDAC2HDAC8 | |
| Cyclopropane SCHEMBL11855589 | 0.84 | HDAC8 (0.59) | HDAC3HDAC4HDAC1HDAC2HDAC8 | |
| Cyclopropane SCHEMBL11843649 | 0.84 | CA12 (0.50) | HDAC3HDAC4HDAC1HDAC2HDAC8 | |
| Cyclopropane SCHEMBL11853761 | 0.84 | HDAC8 (0.62) | HDAC3HDAC4HDAC1HDAC2HDAC8 | |
| Maleic Anhydride SCHEMBL28146128 | 0.83 | HDAC3 (0.50) | HDAC3HDAC4HDAC1HDAC2HDAC8 | |
| Cyclopropane SCHEMBL11852339 | 0.82 | CYP1A2 (0.53) | MAOBALDH1A1CYP1A2CYP2D6MAPT |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-3975429-A | Cyclopropanemethyl esters of cinnamic acid and derivatives thereof | ZOECON CORPORATION (US) | 1976-08-17 | — | — | US | disclosed |