SCHEMBL523185

SCHEMBL523185

COC(=O)C=CC=Cc1ccccc1

nearest known ligand 0.62

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
HDAC3 O15379 3/20 0.62
HDAC4 P56524 3/20 0.62
HDAC1 Q13547 3/20 0.62
HDAC2 Q92769 3/20 0.62
HDAC8 Q9BY41 3/20 0.62
HDAC6 Q9UBN7 3/20 0.62
HDAC7 Q8WUI4 2/20 0.62
HDAC10 Q969S8 2/20 0.62
HDAC11 Q96DB2 2/20 0.62
HDAC9 Q9UKV0 2/20 0.62
HDAC5 Q9UQL6 2/20 0.62
MAOB P27338 6/20 0.57
CA12 O43570 1/20 0.53
CA1 P00915 1/20 0.53
CA2 P00918 1/20 0.53
TYR P14679 1/20 0.53
CA7 P43166 1/20 0.53
CA9 Q16790 1/20 0.53
CA14 Q9ULX7 1/20 0.53
ALDH1A1 P00352 3/20 0.51

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL14080887 1.00 HDAC3 (0.62) HDAC3HDAC4HDAC1HDAC2HDAC8
SCHEMBL523184 1.00 HDAC3 (0.62) HDAC3HDAC4HDAC1HDAC2HDAC8
SCHEMBL15164766 0.98 HDAC3 (0.61) HDAC3HDAC4HDAC1HDAC2HDAC8
Cyclopropane SCHEMBL11858366 0.95 HDAC3 (0.57) HDAC3HDAC4HDAC1HDAC2HDAC8
Maleic Anhydride SCHEMBL28146128 0.88 HDAC3 (0.50) HDAC3HDAC4HDAC1HDAC2HDAC8
Triphosphate SCHEMBL28013064 0.87 HDAC3 (0.49) HDAC3HDAC4HDAC1HDAC2HDAC8
E-Methyl Cinnamate SCHEMBL101530 0.86 CA12 (0.69) HDAC3HDAC4HDAC1HDAC2HDAC8
E-Methyl Cinnamate SCHEMBL901224 0.86 CA12 (0.69) HDAC3HDAC4HDAC1HDAC2HDAC8
E-Methyl Cinnamate SCHEMBL1862419 0.86 CA12 (0.69) HDAC3HDAC4HDAC1HDAC2HDAC8
E-Methyl Cinnamate SCHEMBL112062 0.86 CA12 (0.69) HDAC3HDAC4HDAC1HDAC2HDAC8

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 17 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
CN-115298159-A Treatment of disorders associated with oxidative stress and compounds therefor 阿德莱德大学 2022-11-04 CN disclosed
CN-110437054-A A kind of cobalt complex selective hydration α, the method for beta-unsaturated carbonyl compound WANHUA CHEMICAL GROUP CO LTD 2019-11-12 CN disclosed
CN-105944693-A Amide-containing adsorption material and synthesis method thereof 张国华 2016-09-21 CN disclosed
CN-105820282-A High-stability hydrogen bond donor and acceptor containing macroporous adsorbent resin and synthetic method thereof 西安蓝深环保科技有限公司 2016-08-03 CN disclosed
EP-2417082-B1 CATALYTIC WITTIG AND MITSUNOBU REACTIONS UNIV TEXAS (US) 2016-03-16 EP disclosed
CN-102438970-B Wittig reaction and the light of catalysis prolong reaction BOARD OF REGENTS THE UNIVERSITY OF TEXAS SYSTEM (US) 2015-10-14 CN disclosed
US-8901365-B2 Catalytic Wittig and Mitsunobu reactions BOARD OF REGENTS, THE UNIVERSITY OF TEXAS SYSTEM (US) 2014-12-02 US disclosed
CN-102438970-A Catalytic wittig and mitsunobu reactions UNIV TEXAS 2012-05-02 CN disclosed
EP-2417082-A2 CATALYTIC WITTIG AND MITSUNOBU REACTIONS THE BOARD OF REGENTS, THE UNIVERSITY OF TEXAS SYSTEM (US) 2012-02-15 EP disclosed
US-20120029211-A1 Catalytic Wittig and Mitsunobu Reactions THE UNIVERSITY OF TEXAS AT ARLINGTON 2012-02-02 US disclosed
WO-2010118042-A2 CATALYTIC WITTIG AND MITSUNOBU REACTIONS BOARD OF REGENTS THE UNIVERSITY OF TEXAS AT ARLINGTON (US) 2010-10-14 WO disclosed
CN-100426143-C Image shaping method and instrument, receiving paper for electronic camera image and printed matter of electronic camera FUJI PHOTO FILM CO LTD (JP) 2008-10-15 CN disclosed
CN-1530760-A Image shaping method and instrument, receiving paper for electronic camera image and printed matter of electronic camera ��ʿ��Ƭ��ʽ���� 2004-09-22 CN disclosed
CN-1499301-A Cleaning method and image forming instrument ��ʿ��Ƭ��ʽ���� 2004-05-26 CN disclosed
CN-1497497-A Method for producing authentication identification card and transfer foil for protecting card surface used for the same 柯尼卡美能达控股株式会社 2004-05-19 CN disclosed
CN-1125046-C Butadiene derivatives and process for producing the same TANABE SEIYAKU CO (JP) 2003-10-22 CN disclosed
CN-1214678-A Butadiene derivatives and process for preparing thereof TANABE SEIYAKU CO (JP) 1999-04-21 CN disclosed