Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 8/20 | 0.61 |
| ▸ | HSD17B10 | Q99714 | 8/20 | 0.61 |
| ▸ | MAPT | P10636 | 7/20 | 0.61 |
| ▸ | KDM4E | B2RXH2 | 5/20 | 0.61 |
| ▸ | TDP1 | Q9NUW8 | 5/20 | 0.61 |
| ▸ | HPGD | P15428 | 4/20 | 0.61 |
| ▸ | CYP3A4 | P08684 | 4/20 | 0.61 |
| ▸ | KMT2A | Q03164 | 4/20 | 0.61 |
| ▸ | MEN1 | O00255 | 3/20 | 0.61 |
| ▸ | SLC15A2 | Q16348 | 3/20 | 0.61 |
| ▸ | CYP2C9 | P11712 | 2/20 | 0.61 |
| ▸ | NR1I2 | O75469 | 2/20 | 0.61 |
| ▸ | LMNA | P02545 | 2/20 | 0.61 |
| ▸ | MAPK1 | P28482 | 2/20 | 0.61 |
| ▸ | BLM | P54132 | 1/20 | 0.61 |
| ▸ | ADORA3 | P0DMS8 | 1/20 | 0.61 |
| ▸ | CTDSP1 | Q9GZU7 | 1/20 | 0.61 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.61 |
| ▸ | ADRA1A | P35348 | 1/20 | 0.61 |
| ▸ | HTR2B | P41595 | 1/20 | 0.61 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL11856301 | 1.00 | ALDH1A1 (0.61) | ALDH1A1HSD17B10MAPTKDM4ETDP1 | |
| SCHEMBL11691615 | 0.92 | ALDH1A1 (0.57) | ALDH1A1HSD17B10MAPTKDM4ETDP1 | |
| SCHEMBL11691602 | 0.92 | ALDH1A1 (0.57) | ALDH1A1HSD17B10MAPTKDM4ETDP1 | |
| SCHEMBL11865087 | 0.91 | HSD17B10 (0.63) | ALDH1A1HSD17B10MAPTKDM4ETDP1 | |
| SCHEMBL11865083 | 0.91 | HSD17B10 (0.63) | ALDH1A1HSD17B10MAPTKDM4ETDP1 | |
| SCHEMBL11870051 | 0.91 | ALDH1A1 (0.59) | ALDH1A1HSD17B10MAPTKDM4ETDP1 | |
| SCHEMBL11858543 | 0.91 | ALDH1A1 (0.59) | ALDH1A1HSD17B10MAPTKDM4ETDP1 | |
| SCHEMBL11860389 | 0.88 | MAPT (0.79) | ALDH1A1HSD17B10MAPTKDM4ETDP1 | |
| SCHEMBL11159809 | 0.88 | HSD17B10 (0.79) | ALDH1A1HSD17B10MAPTKDM4ETDP1 | |
| SCHEMBL11858254 | 0.88 | ALDH1A1 (0.60) | ALDH1A1HSD17B10MAPTKDM4ETDP1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-3953436-A | 3,4-Dicarboxycephalosporins and derivatives | ELI LILLY AND COMPANY (US) | 1976-04-27 | — | — | US | disclosed |