Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | LMNA | P02545 | 2/20 | 0.67 |
| ▸ | ABCC4 | O15439 | 2/20 | 0.67 |
| ▸ | POLB | P06746 | 2/20 | 0.67 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.67 |
| ▸ | PGR | P06401 | 1/20 | 0.67 |
| ▸ | MAPT | P10636 | 1/20 | 0.67 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.67 |
| ▸ | ABCB11 | O95342 | 1/20 | 0.67 |
| ▸ | PTGIR | P43119 | 8/20 | 0.58 |
| ▸ | PTGER2 | P43116 | 6/20 | 0.58 |
| ▸ | TSHR | P16473 | 2/20 | 0.56 |
| ▸ | PTGER4 | P35408 | 2/20 | 0.56 |
| ▸ | MEN1 | O00255 | 1/20 | 0.56 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.56 |
| ▸ | HPGD | P15428 | 1/20 | 0.56 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.56 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.56 |
| ▸ | ABCC3 | O15438 | 1/20 | 0.56 |
| ▸ | RARB | P10826 | 1/20 | 0.56 |
| ▸ | RARG | P13631 | 1/20 | 0.56 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL11743269 | 1.00 | LMNA (0.67) | LMNAABCC4POLBALDH1A1PGR | |
| SCHEMBL11859148 | 0.99 | LMNA (0.66) | LMNAABCC4POLBALDH1A1PGR | |
| SCHEMBL11859156 | 0.99 | LMNA (0.66) | LMNAABCC4POLBALDH1A1PGR | |
| SCHEMBL11859163 | 0.99 | LMNA (0.66) | LMNAABCC4POLBALDH1A1PGR | |
| SCHEMBL11868211 | 0.90 | LMNA (0.56) | LMNAABCC4POLBALDH1A1PGR | |
| SCHEMBL11868216 | 0.90 | LMNA (0.56) | LMNAABCC4POLBALDH1A1PGR | |
| SCHEMBL11868224 | 0.90 | LMNA (0.56) | LMNAABCC4POLBALDH1A1PGR | |
| SCHEMBL11866030 | 0.88 | PTGIR (0.71) | LMNAABCC4POLBALDH1A1PGR | |
| SCHEMBL7744902 | 0.88 | PTGIR (0.71) | LMNAABCC4POLBALDH1A1PGR | |
| SCHEMBL9487052 | 0.88 | PTGIR (0.71) | LMNAABCC4POLBALDH1A1PGR |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-3992411-A | 2α-Formyl-3β-[(methoxalyl)oxy]-5-oxo-1β-cyclopentaneheptanoic acid and process | MERCK & CO., INC. (US) | 1976-11-16 | — | — | US | disclosed |