Predicted protein targets (top 19)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MAPT | P10636 | 3/20 | 0.86 |
| ▸ | SMN1; SMN2 | Q16637 | 3/20 | 0.86 |
| ▸ | ELANE | P08246 | 3/20 | 0.46 |
| ▸ | CA1 | P00915 | 1/20 | 0.44 |
| ▸ | CA9 | Q16790 | 1/20 | 0.44 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.43 |
| ▸ | HTT | P42858 | 3/20 | 0.43 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.43 |
| ▸ | HCAR2 | Q8TDS4 | 2/20 | 0.42 |
| ▸ | TP53 | P04637 | 1/20 | 0.42 |
| ▸ | GAA | P10253 | 1/20 | 0.42 |
| ▸ | TSHR | P16473 | 1/20 | 0.42 |
| ▸ | SIRT2 | Q8IXJ6 | 1/20 | 0.41 |
| ▸ | STS | P08842 | 1/20 | 0.39 |
| ▸ | SRC | P12931 | 1/20 | 0.39 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.38 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.38 |
| ▸ | GPR84 | Q9NQS5 | 2/20 | 0.38 |
| ▸ | EPHX2 | P34913 | 1/20 | 0.37 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL11854128 | 1.00 | MAPT (0.86) | MAPTSMN1; SMN2ELANECA1CA9 | |
| SCHEMBL11858889 | 1.00 | MAPT (0.86) | MAPTSMN1; SMN2ELANECA1CA9 | |
| SCHEMBL27909290 | 1.00 | MAPT (0.86) | MAPTSMN1; SMN2ELANECA1CA9 | |
| SCHEMBL6237632 | 0.98 | MAPT (0.82) | MAPTSMN1; SMN2ELANECA1CA9 | |
| SCHEMBL11779539 | 0.93 | MAPT (0.79) | MAPTSMN1; SMN2ELANECA1CA9 | |
| SCHEMBL30165066 | 0.93 | MAPT (1.00) | MAPTSMN1; SMN2ELANECA1CA9 | |
| SCHEMBL6912180 | 0.81 | MAPT (0.56) | MAPTSMN1; SMN2ELANEALDH1A1HTT | |
| SCHEMBL6914193 | 0.81 | MAPT (0.56) | MAPTSMN1; SMN2ELANEALDH1A1HTT | |
| SCHEMBL6905774 | 0.81 | MAPT (0.56) | MAPTSMN1; SMN2ELANEALDH1A1HTT | |
| SCHEMBL6910732 | 0.81 | MAPT (0.56) | MAPTSMN1; SMN2ELANEALDH1A1HTT |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-3972888-A | Process for the preparation of 1-hydroxy-pyridones | HOECHST AKTIENGESELLSCHAFT (DT) | 1976-08-03 | — | — | US | disclosed |