Predicted protein targets (top 18)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MAPT | P10636 | 4/20 | 0.82 |
| ▸ | SMN1; SMN2 | Q16637 | 4/20 | 0.82 |
| ▸ | CA1 | P00915 | 1/20 | 0.45 |
| ▸ | CA9 | Q16790 | 1/20 | 0.45 |
| ▸ | ALDH1A1 | P00352 | 4/20 | 0.44 |
| ▸ | HTT | P42858 | 3/20 | 0.44 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.44 |
| ▸ | ELANE | P08246 | 3/20 | 0.43 |
| ▸ | TP53 | P04637 | 1/20 | 0.43 |
| ▸ | GAA | P10253 | 1/20 | 0.43 |
| ▸ | TSHR | P16473 | 1/20 | 0.43 |
| ▸ | SIRT2 | Q8IXJ6 | 1/20 | 0.42 |
| ▸ | HCAR2 | Q8TDS4 | 2/20 | 0.41 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.39 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.39 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.37 |
| ▸ | STS | P08842 | 1/20 | 0.37 |
| ▸ | SRC | P12931 | 1/20 | 0.37 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL27909290 | 0.98 | MAPT (0.86) | MAPTSMN1; SMN2CA1CA9ALDH1A1 | |
| SCHEMBL11854128 | 0.98 | MAPT (0.86) | MAPTSMN1; SMN2CA1CA9ALDH1A1 | |
| SCHEMBL11859633 | 0.98 | MAPT (0.86) | MAPTSMN1; SMN2CA1CA9ALDH1A1 | |
| SCHEMBL11858889 | 0.98 | MAPT (0.86) | MAPTSMN1; SMN2CA1CA9ALDH1A1 | |
| SCHEMBL11779539 | 0.94 | MAPT (0.79) | MAPTSMN1; SMN2CA1CA9ALDH1A1 | |
| SCHEMBL30165066 | 0.90 | MAPT (1.00) | MAPTSMN1; SMN2CA1CA9ALDH1A1 | |
| SCHEMBL2782253 | 0.80 | MAPT (0.53) | MAPTSMN1; SMN2ALDH1A1HTTALOX15 | |
| SCHEMBL563659 | 0.80 | ALOX15 (0.54) | MAPTSMN1; SMN2ALDH1A1HTTALOX15 | |
| SCHEMBL11847254 | 0.80 | MAPT (0.72) | MAPTSMN1; SMN2CA1CA9HCAR2 | |
| SCHEMBL6905774 | 0.79 | MAPT (0.56) | MAPTSMN1; SMN2ALDH1A1HTTALOX15 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 24 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1024695-B1 | FUNGICIDE COMPRISING 4-METHYL-6-PENTYL-2H-PYRAN-2-ONE | CUTLER HORACE G (US) | 2005-06-22 | — | — | EP | claimed |
| EP-1024695-A4 | FUNGICIDE COMPRISING 4-METHYL-6-PENTYL-2H-PYRAN-2-ONE | CUTLER HORACE G (US) | 2002-04-03 | — | — | EP | claimed |
| US-6251832-B1 | MIXTURE OF FUNGICIDE AND ONE OR MORE CARRIERS, ADJUVANTS AND/OR DILUENTS; FOR AGRICULTURAL OR HORTICULTURAL USE | CUTLER, HORACE G. | 2001-06-26 | — | — | US | claimed |
| EP-1024695-A1 | FUNGICIDE COMPRISING 4-METHYL-6-PENTYL-2H-PYRAN-2-ONE | Cutler, Horace G. (US) | 2000-08-09 | — | — | EP | claimed |
| WO-1999004633-A1 | FUNGICIDE COMPRISING 4-METHYL-6-PENTYL-2H-PYRAN-2-ONE | THE HORTICULTURE AND FOOD RESEARCH INSTITUTE OF NEW ZEALAND LIMITED (NZ) | 1999-02-04 | — | — | WO | claimed |
| US-11753379-B2 | Process for forming 2-hydroxypyridine-1-oxide or derivatives thereof | CLARIANT INTERNATIONAL LTD (CH) | 2023-09-12 | — | — | US | disclosed |
| CN-110372654-B | Method for synthesizing 4-methyl-6- (2, 4-trimethyl amyl) -2H-pyran-2-ketone by two-step method | 成武县晨晖环保科技有限公司 | 2023-05-23 | — | — | CN | disclosed |
| EP-1024695-B1 | FUNGICIDE COMPRISING 4-METHYL-6-PENTYL-2H-PYRAN-2-ONE | CUTLER HORACE G (US) | 2005-06-22 | — | — | EP | disclosed |
| EP-1024695-B1 | FUNGICIDE COMPRISING 4-METHYL-6-PENTYL-2H-PYRAN-2-ONE | CUTLER HORACE G (US) | 2005-06-22 | — | — | EP | disclosed |
| EP-1024695-A4 | FUNGICIDE COMPRISING 4-METHYL-6-PENTYL-2H-PYRAN-2-ONE | CUTLER HORACE G (US) | 2002-04-03 | — | — | EP | disclosed |
| EP-1024695-A4 | FUNGICIDE COMPRISING 4-METHYL-6-PENTYL-2H-PYRAN-2-ONE | CUTLER HORACE G (US) | 2002-04-03 | — | — | EP | disclosed |
| WO-2001051481-A1 | METHOD FOR THE SYNTHESIS OF 6N-PENTYL-2H-PYRAN-2-ONE | CENTRE NATIONAL DE LA RECHERCHE SCIENTIFIQUE (CNRS) (FR) | 2001-07-19 | — | — | WO | disclosed |
| EP-1024695-A1 | FUNGICIDE COMPRISING 4-METHYL-6-PENTYL-2H-PYRAN-2-ONE | Cutler, Horace G. (US) | 2000-08-09 | — | — | EP | disclosed |
| WO-1999004633-A1 | FUNGICIDE COMPRISING 4-METHYL-6-PENTYL-2H-PYRAN-2-ONE | THE HORTICULTURE AND FOOD RESEARCH INSTITUTE OF NEW ZEALAND LIMITED (NZ) | 1999-02-04 | — | — | WO | disclosed |
| WO-1999004633-A1 | FUNGICIDE COMPRISING 4-METHYL-6-PENTYL-2H-PYRAN-2-ONE | THE HORTICULTURE AND FOOD RESEARCH INSTITUTE OF NEW ZEALAND LIMITED (NZ) | 1999-02-04 | — | — | WO | disclosed |
| US-5137035-A | With combustible filler of natural tobacco, reconstituted tobacco or tobacco substitutes | PHILIP MORRIS INCORPORATED (US) | 1992-08-11 | — | — | US | disclosed |
| US-5120368-A | VANILLIN 5-HYDROXYESTERS AND SMOKING COMPOSITIONS CONTAINING A VANILLIN-RELEASE ADDITIVE | PHILIP MORRIS INCORPORATED (US) | 1992-06-09 | — | — | US | disclosed |
| US-5114493-A | Smoking compositions containing a hexahydrobenzofuranone flavorant | PHILIP MORRIS INC. (US) | 1992-05-19 | — | — | US | disclosed |
| EP-0470766-A2 | Smoking composition containing a vanillin-release additive | Philip Morris Products Inc. (US) | 1992-02-12 | — | — | EP | disclosed |
| US-4690157-A | DERIVATIVES OF BUTYROLACTONE OR VALEROLACTONE; CIGARETTES | PHILIP MORRIS INCORPORATED (US) | 1987-09-01 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-11753379-B2 | Process for forming 2-hydroxypyridine-1-oxide or derivatives thereof | HMOX2, HMOX1, HPD | MAPT 4348/4885SMN1; SMN2 1390/4885CA1 1693/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.