Predicted protein targets (top 18)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CA9 | Q16790 | 12/20 | 0.56 |
| ▸ | CA12 | O43570 | 11/20 | 0.56 |
| ▸ | CA1 | P00915 | 11/20 | 0.56 |
| ▸ | CA2 | P00918 | 11/20 | 0.56 |
| ▸ | CA14 | Q9ULX7 | 5/20 | 0.56 |
| ▸ | NFKB1 | P19838 | 3/20 | 0.50 |
| ▸ | POLB | P06746 | 1/20 | 0.49 |
| ▸ | TXN | P10599 | 1/20 | 0.47 |
| ▸ | MAPT | P10636 | 3/20 | 0.46 |
| ▸ | MEN1 | O00255 | 2/20 | 0.46 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.46 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.46 |
| ▸ | CACNA1B | Q00975 | 1/20 | 0.46 |
| ▸ | APBA1 | Q02410 | 1/20 | 0.46 |
| ▸ | CA5A | P35218 | 1/20 | 0.45 |
| ▸ | CA5B | Q9Y2D0 | 1/20 | 0.45 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.44 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.44 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL114234 | 0.79 | CA9 (0.71) | CA9CA12CA1CA2CA14 | |
| SCHEMBL4572353 | 0.78 | NFKB1 (0.58) | CA9CA12CA1CA2CA14 | |
| SCHEMBL1336547 | 0.78 | CA9 (0.69) | CA9CA12CA1CA2CA14 | |
| SCHEMBL11837292 | 0.77 | NFKB1 (0.78) | CA9CA12CA1CA2CA14 | |
| SCHEMBL11441071 | 0.75 | NFKB1 (0.58) | CA9CA12CA1CA2CA14 | |
| SCHEMBL6394050 | 0.73 | JAK3 (0.48) | CA9CA12CA1CA2CA14 | |
| SCHEMBL4143822 | 0.73 | JAK3 (0.48) | CA9CA12CA1CA2CA14 | |
| SCHEMBL18475432 | 0.72 | CA9 (1.00) | CA9CA12CA1CA2CA14 | |
| SCHEMBL1336549 | 0.72 | CA9 (0.71) | CA9CA12CA1CA2CA14 | |
| SCHEMBL4581953 | 0.72 | NFKB1 (0.70) | CA9CA12CA1CA2CA14 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-3994906-A | DYE COUPLERS | CIBA-GEIGY AG (CH) | 1976-11-30 | — | — | US | disclosed |