Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MAPT | P10636 | 3/20 | 0.50 |
| ▸ | SMN1; SMN2 | Q16637 | 3/20 | 0.50 |
| ▸ | KMT2A | Q03164 | 3/20 | 0.40 |
| ▸ | KDM4E | B2RXH2 | 3/20 | 0.40 |
| ▸ | CA1 | P00915 | 1/20 | 0.38 |
| ▸ | CA9 | Q16790 | 1/20 | 0.38 |
| ▸ | RAB9A | P51151 | 2/20 | 0.35 |
| ▸ | NPC1 | O15118 | 1/20 | 0.35 |
| ▸ | THRB | P10828 | 1/20 | 0.33 |
| ▸ | MEN1 | O00255 | 1/20 | 0.33 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.33 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.33 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.33 |
| ▸ | ALDH1A1 | P00352 | 4/20 | 0.32 |
| ▸ | HTT | P42858 | 1/20 | 0.32 |
| ▸ | USP2 | O75604 | 1/20 | 0.32 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.32 |
| ▸ | GAA | P10253 | 1/20 | 0.32 |
| ▸ | TSHR | P16473 | 1/20 | 0.32 |
| ▸ | KDM4C | Q9H3R0 | 1/20 | 0.31 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL11861951 | 0.73 | MAPT (0.46) | MAPTSMN1; SMN2KMT2AKDM4ECA1 | |
| SCHEMBL11867587 | 0.72 | ALDH1A1 (0.37) | SMN1; SMN2KDM4ERAB9ANPC1THRB | |
| SCHEMBL11864743 | 0.70 | MAPT (0.41) | MAPTSMN1; SMN2KMT2AKDM4ECA1 | |
| SCHEMBL10961859 | 0.69 | MAPT (0.62) | MAPTSMN1; SMN2KMT2AKDM4ECA1 | |
| SCHEMBL11527449 | 0.69 | KMT2A (0.36) | KMT2A | |
| SCHEMBL11857804 | 0.69 | ALDH1A1 (0.35) | SMN1; SMN2KDM4ERAB9AALDH1A1GAA | |
| SCHEMBL11857584 | 0.68 | MAPT (0.51) | MAPTSMN1; SMN2KMT2AKDM4ECA1 | |
| SCHEMBL30165066 | 0.68 | MAPT (1.00) | MAPTSMN1; SMN2KMT2AKDM4ECA1 | |
| SCHEMBL5024307 | 0.67 | SMN1; SMN2 (0.56) | SMN1; SMN2KMT2AKDM4ERAB9ANPC1 | |
| SCHEMBL10961858 | 0.67 | MAPT (0.64) | MAPTSMN1; SMN2KMT2AKDM4ECA1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-3969323-A | Photo-crosslinkable 2-pyrone polymers and processes for the manufacture thereof | HOECHST AKTIENGESELLSCHAFT (DT) | 1976-07-13 | — | — | US | disclosed |