Predicted protein targets (top 12)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | GSK3B | P49841 | 10/20 | 1.00 |
| ▸ | PTPN1 | P18031 | 5/20 | 0.64 |
| ▸ | ERCC5 | P28715 | 1/20 | 0.55 |
| ▸ | FEN1 | P39748 | 1/20 | 0.55 |
| ▸ | CES2 | O00748 | 1/20 | 0.54 |
| ▸ | CES1 | P23141 | 1/20 | 0.54 |
| ▸ | MAPT | P10636 | 1/20 | 0.53 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.53 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.52 |
| ▸ | TSHR | P16473 | 1/20 | 0.52 |
| ▸ | NPC1 | O15118 | 1/20 | 0.52 |
| ▸ | RAB9A | P51151 | 1/20 | 0.52 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL5165015 | 0.94 | GSK3B (0.88) | GSK3BPTPN1ERCC5FEN1CES2 | |
| SCHEMBL1283602 | 0.88 | GSK3B (0.78) | GSK3BPTPN1ERCC5FEN1 | |
| SCHEMBL205280 | 0.87 | GSK3B (0.80) | GSK3BPTPN1NPC1RAB9A | |
| SCHEMBL29130566 | 0.84 | GSK3B (0.70) | GSK3BPTPN1ERCC5FEN1CES2 | |
| SCHEMBL6276851 | 0.82 | GSK3B (0.69) | GSK3BERCC5FEN1CES2CES1 | |
| SCHEMBL7500366 | 0.81 | NR4A2 (0.69) | GSK3BPTPN1MAPTNPC1RAB9A | |
| SCHEMBL16552727 | 0.80 | GSK3B (0.70) | GSK3BERCC5FEN1CES2CES1 | |
| SCHEMBL28594745 | 0.80 | GSK3B (0.70) | GSK3BPTPN1MAPT | |
| SCHEMBL689331 | 0.80 | GSK3B (0.83) | GSK3BPTPN1ERCC5FEN1MAPT | |
| SCHEMBL600674 | 0.80 | ERCC5 (0.72) | GSK3BERCC5FEN1CES2CES1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Appears in 2189 patents — a generic fragment claimed broadly, so it's down-weighted as IP noise. Top by claim status then date:
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-119930621-A | Fungus-inhibiting matrine hydrazine thiazole derivative and preparation method and application thereof | 南京林业大学 | 2025-05-06 | — | — | CN | claimed |
| CN-116262673-B | Preparation method of alpha-bromoacetophenone compound | 浙江工业大学 | 2025-04-29 | — | — | CN | claimed |
| CN-119661533-A | Fungus-inhibiting matrine derivative, preparation method and application | 南京林业大学 | 2025-03-21 | — | — | CN | claimed |
| CN-118930487-A | 1,3, 5-Trisubstituted pyrazole compound and preparation method thereof | 赣南师范大学 | 2024-11-12 | — | — | CN | claimed |
| EP-3959200-B1 | NEW TRIAZOLE AND TRIAZOLOTHIADIAZINE DERIVATIVES EXERTING CYTOTOXIC AND APOPTOTIC EFFECTS ON A549 CELLS THROUGH AKT INHIBITION | ANADOLU UNIV (TR) | 2024-03-20 | — | — | EP | claimed |
| EP-3958980-B1 | TARGETED NOVEL TRIAZOLOTHIADIAZINE DERIVATIVES FOR THE TREATMENT OF LUNG CANCER | ANADOLU UNIV (TR) | 2023-11-15 | — | — | EP | claimed |
| CN-116217501-A | Method for efficiently synthesizing nitrogen-containing heterocyclic compound | 东华理工大学 | 2023-06-06 | — | — | CN | claimed |
| EP-3959200-A1 | NEW TRIAZOLE AND TRIAZOLOTHIADIAZINE DERIVATIVES EXERTING CYTOTOXIC AND APOPTOTIC EFFECTS ON A549 CELLS THROUGH AKT INHIBITION | Anadolu Universitesi (TR) | 2022-03-02 | — | — | EP | claimed |
| EP-3958980-A1 | TARGETED NOVEL TRIAZOLOTHIADIAZINE DERIVATIVES FOR THE TREATMENT OF LUNG CANCER | Anadolu Universitesi (TR) | 2022-03-02 | — | — | EP | claimed |
| WO-2022005414-A1 | NEW TRIAZOLE AND TRIAZOLOTHIADIAZINE DERIVATIVES EXERTING CYTOTOXIC AND APOPTOTIC EFFECTS ON A549 CELLS THROUGH AKT INHIBITION | ANADOLU UNIVERSITESI (TR) | 2022-01-06 | — | — | WO | claimed |
| US-20110196160-A1 | SYNTHESIS OF (2S-CIS)-2-(BROMOMETHYL)-2-(4-CHLOROPHENYL)-1,3 DIOXOLANE-4-METHANOL METHANESULFONATE(ESTER) | JANSSEN PHARMACEUTICA, NV (BE) | 2011-08-11 | — | — | US | claimed |
| EP-2325178-A1 | PROCESS FOR PRODUCTION OF OPTICALLY ACTIVE COMPOUND | DAISO CO., LTD. (JP) | 2011-05-25 | — | — | EP | claimed |
| EP-2152698-B1 | IMPROVED SYNTHESIS OF (2S-CIS)-2-(BROMOMETHYL)-2-(4-CHLOROPHENYL)-1,3 DIOXOLANE-4-METHANOL METHANESULFONATE(ESTER) | JANSSEN PHARMACEUTICA NV (BE) | 2010-07-21 | — | — | EP | claimed |
| US-20020061895-A1 | 6-fluoro-1,4-dihydro-7-[4-(2-hydroxyiminoethyl)-1-piperazinyl]-4-oxoquinoline-3-carboxylic acid derivatives, their preparation and pharmaceutical compositions | PHARMACEUTICAL INDUSTRY TECHNOLOGY | 2002-05-23 | — | — | US | claimed |
| EP-0575370-B1 | PROCESS FOR THE PURIFICATION OF LOFEPRAMINE BY CRYSTALLISATION | SCHULER WILHELM (DE) | 1996-04-24 | — | — | EP | claimed |
| EP-0341066-B1 | Immunostimulating guanine derivatives, compositions and methods | SCRIPPS CLINIC RES (US) | 1994-11-09 | — | — | EP | claimed |
| EP-0575370-A1 | PROCESS FOR THE PURIFICATION OF LOFEPRAMINE BY CRYSTALLISATION. | SCHULER WILHELM (DE) | 1993-12-29 | — | — | EP | claimed |
| WO-1992019599-A1 | PROCESS FOR THE PURIFICATION OF LOFEPRAMINE BY CRYSTALLISATION | JELLALABAD LTD. (IE) | 1992-11-12 | — | — | WO | claimed |
| EP-0341066-A2 | Immunostimulating guanine derivatives, compositions and methods | SCRIPPS CLINIC AND RESEARCH FOUNDATION (US) | 1989-11-08 | — | — | EP | claimed |
| US-4172074-A | Preparation of an antidepressant | AKTIEBOLAGET LEO (SE) | 1979-10-23 | — | — | US | claimed |