Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | RAD52 | P43351 | 1/20 | 0.59 |
| ▸ | GAA | P10253 | 1/20 | 0.47 |
| ▸ | KMT2A | Q03164 | 3/20 | 0.47 |
| ▸ | MEN1 | O00255 | 2/20 | 0.47 |
| ▸ | POLB | P06746 | 2/20 | 0.47 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.47 |
| ▸ | LMNA | P02545 | 2/20 | 0.47 |
| ▸ | MITF | O75030 | 1/20 | 0.47 |
| ▸ | HTT | P42858 | 1/20 | 0.47 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.47 |
| ▸ | TSHR | P16473 | 2/20 | 0.45 |
| ▸ | CA12 | O43570 | 1/20 | 0.43 |
| ▸ | CA2 | P00918 | 1/20 | 0.43 |
| ▸ | CA9 | Q16790 | 1/20 | 0.43 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.42 |
| ▸ | HPGD | P15428 | 1/20 | 0.42 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.42 |
| ▸ | CACNA1G | O43497 | 1/20 | 0.42 |
| ▸ | CACNA1H | O95180 | 1/20 | 0.42 |
| ▸ | CACNA1I | Q9P0X4 | 1/20 | 0.42 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| Hydrochloric Acid SCHEMBL11866659 | 0.99 | RAD52 (0.58) | RAD52GAAKMT2AMEN1POLB | |
| Hydrochloric Acid SCHEMBL11864379 | 0.86 | RAD52 (0.56) | RAD52KMT2AALDH1A1LMNASMN1; SMN2 | |
| SCHEMBL11859057 | 0.81 | RAD52 (0.64) | RAD52KMT2APOLBALDH1A1LMNA | |
| Hydrochloric Acid SCHEMBL11865925 | 0.81 | RAD52 (0.63) | RAD52KMT2APOLBALDH1A1LMNA | |
| SCHEMBL11857626 | 0.80 | RAD52 (0.57) | RAD52KMT2APOLBALDH1A1LMNA | |
| SCHEMBL11867802 | 0.80 | MAPT (0.52) | KMT2AMEN1ALDH1A1HTTCA2 | |
| SCHEMBL11859430 | 0.79 | RAD52 (0.75) | RAD52GAAKMT2AALDH1A1SMN1; SMN2 | |
| Hydrochloric Acid SCHEMBL11854978 | 0.78 | RAD52 (0.74) | RAD52GAAKMT2AALDH1A1SMN1; SMN2 | |
| Iodomethane SCHEMBL11870131 | 0.77 | RAD52 (0.73) | RAD52GAAKMT2AALDH1A1SMN1; SMN2 | |
| Hydrochloric Acid SCHEMBL11868391 | 0.77 | RAD52 (0.63) | RAD52GAAKMT2APOLBALDH1A1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-3940418-A | Esters and amides of 4,5-dihydrobenz[g]indazole-3-carboxylic acids and related compounds | G. D. SEARLE & CO. (US) | 1976-02-24 | — | — | US | claimed |
| US-3940418-A | Esters and amides of 4,5-dihydrobenz[g]indazole-3-carboxylic acids and related compounds | G. D. SEARLE & CO. (US) | 1976-02-24 | — | — | US | disclosed |