Predicted protein targets (top 15)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MEN1 | O00255 | 1/20 | 0.40 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.40 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.40 |
| ▸ | TLR8 | Q9NR97 | 4/20 | 0.35 |
| ▸ | KCNH2 | Q12809 | 1/20 | 0.34 |
| ▸ | PDE7A | Q13946 | 2/20 | 0.34 |
| ▸ | HSD11B1 | P28845 | 1/20 | 0.34 |
| ▸ | CETP | P11597 | 1/20 | 0.33 |
| ▸ | GABRA2 | P47869 | 2/20 | 0.33 |
| ▸ | GABRB2 | P47870 | 2/20 | 0.33 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.32 |
| ▸ | NPC1 | O15118 | 1/20 | 0.32 |
| ▸ | MAPT | P10636 | 1/20 | 0.32 |
| ▸ | CYP19A1 | P11511 | 3/20 | 0.32 |
| ▸ | SPNS2 | Q8IVW8 | 1/20 | 0.31 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL11536037 | 0.80 | TLR8 (0.50) | TLR8HSD11B1CETPALDH1A1NPC1 | |
| SCHEMBL564057 | 0.73 | CETP (0.55) | SMN1; SMN2KCNH2HSD11B1CETPALDH1A1 | |
| SCHEMBL2984817 | 0.73 | CETP (0.55) | SMN1; SMN2KCNH2HSD11B1CETPALDH1A1 | |
| SCHEMBL17153858 | 0.73 | CETP (0.55) | SMN1; SMN2KCNH2HSD11B1CETPALDH1A1 | |
| SCHEMBL3125038 | 0.73 | CETP (0.55) | SMN1; SMN2KCNH2HSD11B1CETPALDH1A1 | |
| SCHEMBL2985804 | 0.72 | CETP (0.52) | MEN1KMT2ASMN1; SMN2HSD11B1CETP | |
| Methyl Alcohol SCHEMBL4850107 | 0.71 | CETP (0.52) | MEN1KMT2ASMN1; SMN2HSD11B1CETP | |
| SCHEMBL11510817 | 0.69 | CETP (0.36) | TLR8KCNH2CETPALDH1A1NPC1 | |
| SCHEMBL27331166 | 0.69 | APLNR (0.36) | SMN1; SMN2PDE7AALDH1A1 | |
| SCHEMBL11512204 | 0.68 | TDP1 (0.47) | CETP |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-3937713-A | Process for the preparation of s-triazolo[3,4-b]benzothiazoles | ELI LILLY AND COMPANY (US) | 1976-02-10 | — | — | US | disclosed |