Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KDM4E | B2RXH2 | 8/20 | 0.58 |
| ▸ | TSHR | P16473 | 3/20 | 0.58 |
| ▸ | ALDH1A1 | P00352 | 11/20 | 0.49 |
| ▸ | MAPT | P10636 | 4/20 | 0.49 |
| ▸ | ALDH1A2 | O94788 | 1/20 | 0.49 |
| ▸ | ALDH2 | P05091 | 1/20 | 0.49 |
| ▸ | ALDH1B1 | P30837 | 1/20 | 0.49 |
| ▸ | ALDH1A3 | P47895 | 1/20 | 0.49 |
| ▸ | HPGD | P15428 | 4/20 | 0.44 |
| ▸ | GAA | P10253 | 2/20 | 0.44 |
| ▸ | HTT | P42858 | 2/20 | 0.44 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.44 |
| ▸ | PPARG | P37231 | 1/20 | 0.44 |
| ▸ | MAPK10 | P53779 | 1/20 | 0.44 |
| ▸ | NCOA2 | Q15596 | 1/20 | 0.44 |
| ▸ | RXFP1 | Q9HBX9 | 1/20 | 0.44 |
| ▸ | HSD17B10 | Q99714 | 2/20 | 0.42 |
| ▸ | POLB | P06746 | 1/20 | 0.42 |
| ▸ | HCAR2 | Q8TDS4 | 2/20 | 0.42 |
| ▸ | HSD17B3 | P37058 | 1/20 | 0.42 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL13824371 | 0.73 | KDM4E (0.46) | KDM4ETSHRALDH1A1ALDH1A2ALDH2 | |
| SCHEMBL2574998 | 0.70 | CYP3A4 (0.46) | KDM4ETSHRALDH1A1MAPTHPGD | |
| SCHEMBL7963459 | 0.68 | ALDH1A1 (0.45) | KDM4ETSHRALDH1A1MAPTHPGD | |
| SCHEMBL1262846 | 0.64 | KMT2A (0.36) | TSHRALDH1A1MAPTHPGDGAA | |
| SCHEMBL11854129 | 0.64 | MAPT (0.64) | KDM4ETSHRALDH1A1MAPTHPGD | |
| SCHEMBL15030959 | 0.64 | ALDH1A1 (0.50) | KDM4ETSHRALDH1A1MAPTHPGD | |
| SCHEMBL3031292 | 0.64 | — | — | |
| SCHEMBL9802626 | 0.63 | ALDH1A1 (0.46) | KDM4ETSHRALDH1A1HPGDGAA | |
| SCHEMBL23520162 | 0.63 | HCAR2 (0.41) | KDM4ETSHRALDH1A1MAPTHPGD | |
| SCHEMBL15842559 | 0.63 | ALDH1A1 (0.51) | KDM4ETSHRALDH1A1MAPTHPGD |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-3972888-A | Process for the preparation of 1-hydroxy-pyridones | HOECHST AKTIENGESELLSCHAFT (DT) | 1976-08-03 | — | — | US | disclosed |