Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | AR | P10275 | 7/20 | 0.52 |
| ▸ | NR3C2 | P08235 | 2/20 | 0.52 |
| ▸ | PGR | P06401 | 6/20 | 0.50 |
| ▸ | CYP17A1 | P05093 | 2/20 | 0.39 |
| ▸ | MAPT | P10636 | 4/20 | 0.38 |
| ▸ | LMNA | P02545 | 3/20 | 0.38 |
| ▸ | NR3C1 | P04150 | 3/20 | 0.36 |
| ▸ | PDE4D | Q08499 | 1/20 | 0.36 |
| ▸ | SERPINA6 | P08185 | 1/20 | 0.35 |
| ▸ | CYP3A4 | P08684 | 3/20 | 0.34 |
| ▸ | CYP2C19 | P33261 | 3/20 | 0.34 |
| ▸ | CYP2C9 | P11712 | 2/20 | 0.34 |
| ▸ | NR1I2 | O75469 | 1/20 | 0.34 |
| ▸ | TSHR | P16473 | 1/20 | 0.34 |
| ▸ | OPRK1 | P41145 | 1/20 | 0.34 |
| ▸ | ESR1 | P03372 | 1/20 | 0.33 |
| ▸ | CHRM2 | P08172 | 1/20 | 0.33 |
| ▸ | ADORA3 | P0DMS8 | 1/20 | 0.33 |
| ▸ | CHRM1 | P11229 | 1/20 | 0.33 |
| ▸ | TBXA2R | P21731 | 1/20 | 0.33 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL6692321 | 1.00 | AR (0.52) | ARNR3C2PGRCYP17A1MAPT | |
| SCHEMBL13397495 | 0.85 | CYP17A1 (0.54) | ARNR3C2PGRCYP17A1MAPT | |
| SCHEMBL12437208 | 0.85 | CYP17A1 (0.54) | ARNR3C2PGRCYP17A1MAPT | |
| SCHEMBL17302786 | 0.85 | CYP17A1 (0.54) | ARNR3C2PGRCYP17A1MAPT | |
| SCHEMBL14200096 | 0.85 | CYP17A1 (0.54) | ARNR3C2PGRCYP17A1MAPT | |
| SCHEMBL12101456 | 0.85 | CYP17A1 (0.54) | ARNR3C2PGRCYP17A1MAPT | |
| SCHEMBL29519614 | 0.85 | CYP17A1 (0.54) | ARNR3C2PGRCYP17A1MAPT | |
| SCHEMBL8843324 | 0.85 | CYP17A1 (0.54) | ARNR3C2PGRCYP17A1MAPT | |
| SCHEMBL13139936 | 0.85 | CYP17A1 (0.54) | ARNR3C2PGRCYP17A1MAPT | |
| SCHEMBL3750546 | 0.85 | CYP17A1 (0.54) | ARNR3C2PGRCYP17A1MAPT |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-3959322-A | Synthesis of 13-alkyl-gon-4-ones | Smith, Herchel (US) | 1976-05-25 | — | — | US | disclosed |