Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TRPA1 | O75762 | 4/20 | 0.54 |
| ▸ | NR4A2 | P43354 | 2/20 | 0.54 |
| ▸ | POLB | P06746 | 3/20 | 0.45 |
| ▸ | POLA1 | P09884 | 1/20 | 0.45 |
| ▸ | PPARG | P37231 | 4/20 | 0.45 |
| ▸ | PPARD | Q03181 | 2/20 | 0.45 |
| ▸ | PPARA | Q07869 | 2/20 | 0.45 |
| ▸ | PTGER2 | P43116 | 4/20 | 0.44 |
| ▸ | PTGER4 | P35408 | 1/20 | 0.44 |
| ▸ | PTGER3 | P43115 | 1/20 | 0.44 |
| ▸ | OXER1 | Q8TDS5 | 2/20 | 0.42 |
| ▸ | ALOX5 | P09917 | 1/20 | 0.42 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.42 |
| ▸ | LMNA | P02545 | 2/20 | 0.42 |
| ▸ | DNTT | P04053 | 1/20 | 0.42 |
| ▸ | PGR | P06401 | 1/20 | 0.42 |
| ▸ | MAPT | P10636 | 1/20 | 0.42 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.42 |
| ▸ | ABCC4 | O15439 | 1/20 | 0.42 |
| ▸ | ABCB11 | O95342 | 1/20 | 0.42 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL11862189 | 1.00 | TRPA1 (0.54) | TRPA1NR4A2POLBPOLA1PPARG | |
| SCHEMBL11862204 | 1.00 | TRPA1 (0.54) | TRPA1NR4A2POLBPOLA1PPARG | |
| SCHEMBL11871423 | 0.89 | TRPA1 (0.55) | TRPA1NR4A2POLBPOLA1PPARG | |
| SCHEMBL11871421 | 0.89 | TRPA1 (0.55) | TRPA1NR4A2POLBPOLA1PPARG | |
| SCHEMBL11869089 | 0.89 | TRPA1 (0.55) | TRPA1NR4A2POLBPOLA1PPARG | |
| SCHEMBL11865207 | 0.85 | TRPA1 (0.49) | TRPA1NR4A2POLBPOLA1PPARG | |
| SCHEMBL11865215 | 0.85 | TRPA1 (0.49) | TRPA1NR4A2POLBPOLA1PPARG | |
| SCHEMBL11857503 | 0.85 | TRPA1 (0.49) | TRPA1NR4A2POLBPOLA1PPARG | |
| SCHEMBL11871813 | 0.84 | TRPA1 (0.77) | TRPA1NR4A2POLBPPARGPPARD | |
| SCHEMBL11871804 | 0.84 | TRPA1 (0.77) | TRPA1NR4A2POLBPPARGPPARD |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-3984455-A | Prostaglandin E1 analogs | THE UPJOHN COMPANY (US) | 1976-10-05 | — | — | US | disclosed |