Predicted protein targets (top 14)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KMT2A | Q03164 | 1/20 | 0.53 |
| ▸ | RAD52 | P43351 | 1/20 | 0.52 |
| ▸ | CNR2 | P34972 | 6/20 | 0.49 |
| ▸ | CNR1 | P21554 | 3/20 | 0.49 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.49 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.47 |
| ▸ | CYP2C9 | P11712 | 2/20 | 0.47 |
| ▸ | CYP2C19 | P33261 | 2/20 | 0.47 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.47 |
| ▸ | MAPT | P10636 | 1/20 | 0.47 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.47 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.47 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.47 |
| ▸ | GAA | P10253 | 2/20 | 0.45 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL11871559 | 0.89 | RAD52 (0.62) | KMT2ARAD52CNR2CNR1ALDH1A1 | |
| SCHEMBL11865957 | 0.89 | RAD52 (0.53) | RAD52CNR2CNR1ALDH1A1 | |
| SCHEMBL5698605 | 0.88 | CNR2 (0.51) | RAD52CNR2CNR1MAPK1ALDH1A1 | |
| SCHEMBL11868523 | 0.87 | RAD52 (0.52) | KMT2ARAD52MAPK1ALDH1A1CYP2C9 | |
| SCHEMBL11867763 | 0.85 | RAD52 (0.70) | KMT2ARAD52ALDH1A1CYP2C19CYP3A4 | |
| SCHEMBL11864104 | 0.83 | RAD52 (0.57) | RAD52CNR2CNR1ALDH1A1CYP2C9 | |
| SCHEMBL11859783 | 0.83 | RAD52 (0.44) | RAD52CNR2CNR1MAPK1ALDH1A1 | |
| SCHEMBL11859533 | 0.83 | RAD52 (0.47) | RAD52CNR2CNR1ALDH1A1GAA | |
| Hydrochloric Acid SCHEMBL11861513 | 0.82 | RAD52 (0.57) | RAD52CNR2CNR1ALDH1A1CYP2C9 | |
| SCHEMBL11865536 | 0.82 | RAD52 (0.61) | KMT2ARAD52CNR2CNR1ALDH1A1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-3940418-A | Esters and amides of 4,5-dihydrobenz[g]indazole-3-carboxylic acids and related compounds | G. D. SEARLE & CO. (US) | 1976-02-24 | — | — | US | disclosed |