Predicted protein targets (top 12)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | RAD52 | P43351 | 1/20 | 0.47 |
| ▸ | GAA | P10253 | 1/20 | 0.43 |
| ▸ | CNR2 | P34972 | 4/20 | 0.41 |
| ▸ | CNR1 | P21554 | 2/20 | 0.41 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.40 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.40 |
| ▸ | TP53 | P04637 | 1/20 | 0.40 |
| ▸ | HPGD | P15428 | 1/20 | 0.40 |
| ▸ | CCNA2 | P20248 | 2/20 | 0.39 |
| ▸ | CDK2 | P24941 | 2/20 | 0.39 |
| ▸ | CCNA1 | P78396 | 2/20 | 0.39 |
| ▸ | IKBKB | O14920 | 1/20 | 0.37 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL11864104 | 0.88 | RAD52 (0.57) | RAD52CNR2CNR1ALDH1A1KDM4E | |
| Hydrochloric Acid SCHEMBL11861513 | 0.87 | RAD52 (0.57) | RAD52CNR2CNR1ALDH1A1KDM4E | |
| SCHEMBL11860266 | 0.85 | RAD52 (0.58) | RAD52CNR2CNR1 | |
| SCHEMBL11859783 | 0.84 | RAD52 (0.44) | RAD52CNR2CNR1ALDH1A1KDM4E | |
| SCHEMBL11865791 | 0.83 | CNR2 (0.47) | RAD52CNR2CNR1HPGD | |
| SCHEMBL11863026 | 0.83 | KMT2A (0.53) | RAD52GAACNR2CNR1ALDH1A1 | |
| SCHEMBL11867074 | 0.83 | RAD52 (0.62) | RAD52CNR2CNR1IKBKB | |
| SCHEMBL11870415 | 0.82 | CNR2 (0.49) | RAD52CNR2CNR1HPGD | |
| SCHEMBL11865693 | 0.81 | PTGS2 (0.47) | RAD52GAACNR2CNR1ALDH1A1 | |
| SCHEMBL5698605 | 0.79 | CNR2 (0.51) | RAD52CNR2CNR1ALDH1A1KDM4E |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-3940418-A | Esters and amides of 4,5-dihydrobenz[g]indazole-3-carboxylic acids and related compounds | G. D. SEARLE & CO. (US) | 1976-02-24 | — | — | US | claimed |
| US-3940418-A | Esters and amides of 4,5-dihydrobenz[g]indazole-3-carboxylic acids and related compounds | G. D. SEARLE & CO. (US) | 1976-02-24 | — | — | US | disclosed |