Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | GABBR2 | O75899 | 2/20 | 0.59 |
| ▸ | GABBR1 | Q9UBS5 | 2/20 | 0.59 |
| ▸ | CA12 | O43570 | 1/20 | 0.56 |
| ▸ | AKR1B10 | O60218 | 1/20 | 0.56 |
| ▸ | CA1 | P00915 | 1/20 | 0.56 |
| ▸ | CA2 | P00918 | 1/20 | 0.56 |
| ▸ | AKR1B1 | P15121 | 1/20 | 0.56 |
| ▸ | CA7 | P43166 | 1/20 | 0.56 |
| ▸ | CA9 | Q16790 | 1/20 | 0.56 |
| ▸ | CA14 | Q9ULX7 | 1/20 | 0.56 |
| ▸ | HMGCR | P04035 | 1/20 | 0.49 |
| ▸ | HTT | P42858 | 2/20 | 0.47 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.47 |
| ▸ | GLA | P06280 | 1/20 | 0.47 |
| ▸ | MAPT | P10636 | 1/20 | 0.47 |
| ▸ | RECQL | P46063 | 1/20 | 0.47 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.47 |
| ▸ | TNFRSF1A | P19438 | 1/20 | 0.47 |
| ▸ | PTGS1 | P23219 | 4/20 | 0.46 |
| ▸ | PTGS2 | P35354 | 4/20 | 0.46 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL6752125 | 0.84 | GABBR2 (0.51) | GABBR2GABBR1CA12AKR1B10CA1 | |
| SCHEMBL5712558 | 0.83 | GABBR2 (0.64) | GABBR2GABBR1CA12CA1CA2 | |
| SCHEMBL5712559 | 0.83 | GABBR2 (0.64) | GABBR2GABBR1CA12CA1CA2 | |
| SCHEMBL9686023 | 0.80 | GABBR2 (0.60) | GABBR2GABBR1HTTTNFRSF1APTGS1 | |
| SCHEMBL6910750 | 0.79 | CYP3A4 (0.61) | GABBR2GABBR1CA12CA1CA2 | |
| SCHEMBL6910749 | 0.79 | CYP3A4 (0.61) | GABBR2GABBR1CA12CA1CA2 | |
| Methane SCHEMBL27465060 | 0.79 | GABBR2 (0.59) | GABBR2GABBR1HMGCRTNFRSF1APTGS1 | |
| SCHEMBL9657108 | 0.79 | GABBR2 (0.72) | GABBR2GABBR1CA1CA2HTT | |
| SCHEMBL6734358 | 0.78 | GABBR2 (0.57) | GABBR2GABBR1TNFRSF1AGPR55ALOX5 | |
| SCHEMBL27904472 | 0.78 | CYP3A4 (0.59) | GABBR2GABBR1CA12CA1CA2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-3953398-A | 3,5-DI-TERT-ALKYL-4-HYDROXYCINNAMIC ACID OR ESTER AS STABILIZER | THE GOODYEAR TIRE & RUBBER COMPANY (US) | 1976-04-27 | — | — | US | disclosed |