Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | SCN1A | P35498 | 3/20 | 0.47 |
| ▸ | SCN2A | Q99250 | 3/20 | 0.47 |
| ▸ | SCN3A | Q9NY46 | 3/20 | 0.47 |
| ▸ | ALDH1A1 | P00352 | 4/20 | 0.42 |
| ▸ | CYP3A4 | P08684 | 2/20 | 0.42 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.42 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.42 |
| ▸ | RAD52 | P43351 | 1/20 | 0.42 |
| ▸ | KDM4E | B2RXH2 | 3/20 | 0.41 |
| ▸ | TP53 | P04637 | 3/20 | 0.41 |
| ▸ | HPGD | P15428 | 2/20 | 0.41 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.40 |
| ▸ | CCNA2 | P20248 | 2/20 | 0.40 |
| ▸ | CDK2 | P24941 | 2/20 | 0.40 |
| ▸ | CCNA1 | P78396 | 2/20 | 0.40 |
| ▸ | LMNA | P02545 | 1/20 | 0.40 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.40 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.40 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.39 |
| ▸ | CHRM2 | P08172 | 2/20 | 0.39 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL11870676 | 0.92 | RAD52 (0.47) | SCN1ASCN2ASCN3AALDH1A1CYP3A4 | |
| SCHEMBL11866224 | 0.90 | SCN1A (0.45) | SCN1ASCN2ASCN3AALDH1A1CYP3A4 | |
| SCHEMBL9837128 | 0.86 | ALDH1A1 (0.56) | ALDH1A1CYP3A4CYP2C9CYP2C19KDM4E | |
| SCHEMBL11870590 | 0.85 | RAD52 (0.57) | SCN1ASCN2ASCN3AALDH1A1RAD52 | |
| SCHEMBL11864104 | 0.83 | RAD52 (0.57) | SCN1ASCN2ASCN3AALDH1A1CYP3A4 | |
| Hydrochloric Acid SCHEMBL11861513 | 0.82 | RAD52 (0.57) | SCN1ASCN2ASCN3AALDH1A1CYP3A4 | |
| Hydrochloric Acid SCHEMBL11864379 | 0.82 | RAD52 (0.56) | ALDH1A1RAD52KDM4ETP53HPGD | |
| SCHEMBL8593062 | 0.78 | ALDH1A1 (0.58) | ALDH1A1CYP3A4CYP2C9CYP2C19KDM4E | |
| SCHEMBL9172754 | 0.77 | PTGER1 (0.47) | CYP2C9CYP2C19CCNA2CDK2CCNA1 | |
| SCHEMBL11864991 | 0.76 | ALDH1A1 (0.54) | ALDH1A1CYP3A4CYP2C9CYP2C19KDM4E |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-3940418-A | Esters and amides of 4,5-dihydrobenz[g]indazole-3-carboxylic acids and related compounds | G. D. SEARLE & CO. (US) | 1976-02-24 | — | — | US | disclosed |