Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 4/20 | 0.42 |
| ▸ | TDP1 | Q9NUW8 | 3/20 | 0.42 |
| ▸ | CYP3A4 | P08684 | 3/20 | 0.42 |
| ▸ | TSHR | P16473 | 2/20 | 0.42 |
| ▸ | HPGD | P15428 | 1/20 | 0.42 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.42 |
| ▸ | HIF1A | Q16665 | 1/20 | 0.42 |
| ▸ | TXNRD1 | Q16881 | 1/20 | 0.42 |
| ▸ | TXNRD3 | Q86VQ6 | 1/20 | 0.42 |
| ▸ | TXNRD2 | Q9NNW7 | 1/20 | 0.42 |
| ▸ | PLK1 | P53350 | 1/20 | 0.41 |
| ▸ | LMNA | P02545 | 4/20 | 0.40 |
| ▸ | MAPK1 | P28482 | 4/20 | 0.39 |
| ▸ | MAPT | P10636 | 4/20 | 0.38 |
| ▸ | GAA | P10253 | 3/20 | 0.38 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.38 |
| ▸ | PTPN5 | P54829 | 1/20 | 0.37 |
| ▸ | POLB | P06746 | 1/20 | 0.37 |
| ▸ | NFKBIA | P25963 | 1/20 | 0.36 |
| ▸ | RELA | Q04206 | 1/20 | 0.36 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8947516 | 0.87 | CYP3A4 (0.40) | ALDH1A1TDP1CYP3A4TSHRHPGD | |
| SCHEMBL8947549 | 0.85 | CYP3A4 (0.43) | ALDH1A1TDP1CYP3A4TSHRHPGD | |
| SCHEMBL8855618 | 0.83 | LMNA (0.54) | ALDH1A1TDP1CYP3A4TSHRHPGD | |
| SCHEMBL8947515 | 0.82 | MAPK1 (0.48) | ALDH1A1TDP1CYP3A4TSHRHPGD | |
| SCHEMBL8855540 | 0.80 | PLK1 (0.43) | ALDH1A1TDP1CYP3A4TSHRHPGD | |
| SCHEMBL11644265 | 0.80 | MAPK1 (0.41) | ALDH1A1TDP1CYP3A4TSHRLMNA | |
| SCHEMBL8855525 | 0.79 | PLK1 (0.53) | ALDH1A1TDP1CYP3A4TSHRHPGD | |
| SCHEMBL11645840 | 0.79 | LMNA (0.42) | ALDH1A1TDP1CYP3A4TSHRHPGD | |
| SCHEMBL8855627 | 0.79 | CYP3A4 (0.43) | ALDH1A1TDP1CYP3A4TSHRHPGD | |
| SCHEMBL11854918 | 0.77 | PLK1 (0.41) | ALDH1A1TDP1CYP3A4TSHRHPGD |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-3980784-A | Control of animal parasites with benzimidazoles | ELI LILLY AND COMPANY (US) | 1976-09-14 | — | — | US | disclosed |