Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MAPT | P10636 | 3/20 | 0.43 |
| ▸ | MDM4 | O15151 | 1/20 | 0.43 |
| ▸ | LMNA | P02545 | 1/20 | 0.43 |
| ▸ | MDM2 | Q00987 | 1/20 | 0.43 |
| ▸ | ATM | Q13315 | 2/20 | 0.39 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.39 |
| ▸ | MMP8 | P22894 | 1/20 | 0.37 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.35 |
| ▸ | RECQL | P46063 | 1/20 | 0.35 |
| ▸ | NAALAD2 | Q9Y3Q0 | 1/20 | 0.35 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.35 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.35 |
| ▸ | MEN1 | O00255 | 1/20 | 0.35 |
| ▸ | LTA4H | P09960 | 1/20 | 0.34 |
| ▸ | ANPEP | P15144 | 1/20 | 0.34 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.34 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.34 |
| ▸ | TSHR | P16473 | 1/20 | 0.34 |
| ▸ | CASP1 | P29466 | 1/20 | 0.34 |
| ▸ | CASP3 | P42574 | 1/20 | 0.34 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL28088781 | 0.91 | MAPT (0.50) | MAPTMDM4LMNAMDM2ATM | |
| SCHEMBL8680909 | 0.91 | MAPT (0.50) | MAPTMDM4LMNAMDM2ATM | |
| SCHEMBL9301284 | 0.91 | MAPT (0.50) | MAPTMDM4LMNAMDM2ATM | |
| Diethyl Pyrocarbonate SCHEMBL11863610 | 0.90 | MAPT (0.45) | MAPTMDM4LMNAMDM2ATM | |
| Diethyl Pyrocarbonate SCHEMBL11863590 | 0.90 | MAPT (0.45) | MAPTMDM4LMNAMDM2ATM | |
| SCHEMBL8624954 | 0.89 | MAPT (0.49) | MAPTMDM4LMNAMDM2ATM | |
| SCHEMBL11863595 | 0.83 | MAPT (0.46) | MAPTMDM4LMNAMDM2ATM | |
| SCHEMBL3987755 | 0.81 | FOLH1 (0.46) | MAPTMDM4LMNAMDM2ATM | |
| SCHEMBL3987754 | 0.81 | FOLH1 (0.46) | MAPTMDM4LMNAMDM2ATM | |
| Potassium Ion SCHEMBL8624951 | 0.81 | MAPT (0.48) | MAPTMDM4LMNAMDM2ATM |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-3989688-A | Process for producing 6-amino penicillanic acid derivatives | BIOCRAFT LABORATORIES, INC. (US) | 1976-11-02 | — | — | US | disclosed |