Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | FOLH1 | Q04609 | 2/20 | 0.46 |
| ▸ | CA12 | O43570 | 2/20 | 0.43 |
| ▸ | CA1 | P00915 | 2/20 | 0.43 |
| ▸ | CA2 | P00918 | 2/20 | 0.43 |
| ▸ | CA7 | P43166 | 2/20 | 0.43 |
| ▸ | CA9 | Q16790 | 2/20 | 0.43 |
| ▸ | CA14 | Q9ULX7 | 2/20 | 0.43 |
| ▸ | NAALAD2 | Q9Y3Q0 | 1/20 | 0.43 |
| ▸ | ATM | Q13315 | 2/20 | 0.41 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.41 |
| ▸ | MAPT | P10636 | 2/20 | 0.40 |
| ▸ | MDM4 | O15151 | 1/20 | 0.40 |
| ▸ | LMNA | P02545 | 1/20 | 0.40 |
| ▸ | MDM2 | Q00987 | 1/20 | 0.40 |
| ▸ | YARS1 | P54577 | 1/20 | 0.39 |
| ▸ | ESR2 | Q92731 | 3/20 | 0.39 |
| ▸ | ESR1 | P03372 | 2/20 | 0.39 |
| ▸ | MIF | P14174 | 1/20 | 0.37 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.35 |
| ▸ | SRC | P12931 | 1/20 | 0.35 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL3987754 | 1.00 | FOLH1 (0.46) | FOLH1CA12CA1CA2CA7 | |
| SCHEMBL9301284 | 0.89 | MAPT (0.50) | NAALAD2ATMKMT2AMAPTMDM4 | |
| SCHEMBL28088781 | 0.89 | MAPT (0.50) | NAALAD2ATMKMT2AMAPTMDM4 | |
| SCHEMBL8680909 | 0.89 | MAPT (0.50) | NAALAD2ATMKMT2AMAPTMDM4 | |
| Potassium Ion SCHEMBL6129087 | 0.88 | CA12 (0.43) | FOLH1CA12CA1CA2CA7 | |
| SCHEMBL9302196 | 0.88 | CA12 (0.43) | FOLH1CA12CA1CA2CA7 | |
| Potassium Ion SCHEMBL4826211 | 0.88 | CA12 (0.43) | FOLH1CA12CA1CA2CA7 | |
| Potassium Ion SCHEMBL31198116 | 0.88 | CA12 (0.43) | FOLH1CA12CA1CA2CA7 | |
| SCHEMBL8624954 | 0.88 | MAPT (0.49) | NAALAD2ATMKMT2AMAPTMDM4 | |
| SCHEMBL5995942 | 0.86 | FOLH1 (0.47) | FOLH1CA12CA1CA2CA7 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 17 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-7622577-B2 | Processes for the preparation of cephalosporin derivatives | CJ CHEILJEDANG CORPORATION (KR) | 2009-11-24 | — | — | US | disclosed |
| US-20090221815-A1 | PROCESSES FOR THE PREPARATION OF CEPHEM DERIVATIVES | CJ CHEILJEDANG CORPORATION (KR) | 2009-09-03 | — | — | US | disclosed |
| US-7544797-B2 | Processes for the preparation of cephem derivatives | CJ CHEILJEDANG CORPORATION (KR) | 2009-06-09 | — | — | US | disclosed |
| EP-1678187-A4 | PROCESSES FOR THE PREPARATION OF CEPHALOSPORIN DERIVATIVES | CJ CORP (KR) | 2007-06-13 | — | — | EP | disclosed |
| EP-1678186-A4 | PROCESSES FOR THE PREPARATION OF CEPHEM DERIVATIVES | CJ CORP (KR) | 2007-04-25 | — | — | EP | disclosed |
| US-20070083042-A1 | Processes for the preparation of cephalosporin derivatives | CJ CORPORATION (KR) | 2007-04-12 | — | — | US | disclosed |
| US-20070060747-A1 | Processes for the preparation of cephem derivatives | CJ CORPORATION (KR) | 2007-03-15 | — | — | US | disclosed |
| US-20060173176-A1 | Process for the preparation of (z)-isomer enriched 7-amino-3-propen-1-yl-3-cephem-4-carboxylic acid | RANBAXY LABORATORIES LIMITED (IN) | 2006-08-03 | — | — | US | disclosed |
| EP-1678187-A1 | PROCESSES FOR THE PREPARATION OF CEPHALOSPORIN DERIVATIVES | CJ Corporation (KR) | 2006-07-12 | — | — | EP | disclosed |
| EP-1678186-A1 | PROCESSES FOR THE PREPARATION OF CEPHEM DERIVATIVES | CJ Corporation (KR) | 2006-07-12 | — | — | EP | disclosed |
| EP-1554288-A1 | PROCESS FOR THE PREPARATION OF (Z)-ISOMER ENRICHED 7-AMINO-3-PROPEN-1-YL-3-CEPHEM-4- CARBOXYLIC ACID | RANBAXY LABORATORIES, LTD. (IN) | 2005-07-20 | — | — | EP | disclosed |
| WO-2005042544-A1 | PROCESSES FOR THE PREPARATION OF CEPHALOSPORIN DERIVATIVES | CJ CORPORATION (KR) | 2005-05-12 | — | — | WO | disclosed |
| WO-2005042543-A1 | PROCESSES FOR THE PREPARATION OF CEPHEM DERIVATIVES | CJ CORPORATION (KR) | 2005-05-12 | — | — | WO | disclosed |
| WO-2004033464-A1 | PROCESS FOR THE PREPARATION OF (Z)-ISOMER ENRICHED 7-AMINO-3-PROPEN-1-YL-3-CEPHEM-4- CARBOXYLIC ACID | RANBAXY LABORATORIES LIMITED (IN) | 2004-04-22 | — | — | WO | disclosed |
| EP-0437566-B1 | PHENYL-GLYCINE DERIVATIVES | CHINOIN GYOGYSZER ES VEGYESZET (HU) | 1994-09-28 | — | — | EP | disclosed |
| US-5338868-A | Reacting glycine derivative with trifluoro methane sulfonic acid derivative at low temperature | CHINOIN GYOGYSZER- ES VEGYESZETI TERMEKEK GYARA RT. (HU) | 1994-08-16 | — | — | US | disclosed |
| US-4072710-A | FROM SILYL ESTER AND THIONYL CHLORIDE | PALOMO COLL A L | 1978-02-07 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (4 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20070060747-A1 | Processes for the preparation of cephem derivatives | CEP170, HAMP, NISCH | FOLH1 781/4885CA12 251/4885CA1 2056/4885 |
| US-20070083042-A1 | Processes for the preparation of cephalosporin derivatives | ADH1C, HSD17B14, ADH1A | FOLH1 1103/4885CA12 1491/4885CA1 2219/4885 |
| US-20060173176-A1 | Process for the preparation of (z)-isomer enriched 7-amino-3-propen-1-yl-3-cephem-4-carboxylic acid | CPNE4, PAH, ALAD | FOLH1 173/4885CA12 689/4885CA1 1069/4885 |
| US-20090221815-A1 | PROCESSES FOR THE PREPARATION OF CEPHEM DERIVATIVES | CEP170, HAMP, NISCH | FOLH1 781/4885CA12 251/4885CA1 2056/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.