Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MAPT | P10636 | 5/20 | 0.63 |
| ▸ | KMT2A | Q03164 | 5/20 | 0.62 |
| ▸ | MEN1 | O00255 | 4/20 | 0.62 |
| ▸ | HTT | P42858 | 2/20 | 0.62 |
| ▸ | RAB9A | P51151 | 1/20 | 0.62 |
| ▸ | LMNA | P02545 | 2/20 | 0.62 |
| ▸ | MITF | O75030 | 1/20 | 0.62 |
| ▸ | XBP1 | P17861 | 1/20 | 0.62 |
| ▸ | PAX8 | Q06710 | 1/20 | 0.62 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.62 |
| ▸ | NOD2 | Q9HC29 | 1/20 | 0.62 |
| ▸ | GAA | P10253 | 2/20 | 0.61 |
| ▸ | TP53 | P04637 | 2/20 | 0.57 |
| ▸ | POLB | P06746 | 1/20 | 0.57 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.57 |
| ▸ | NCOA1 | Q15788 | 1/20 | 0.56 |
| ▸ | NCOA3 | Q9Y6Q9 | 1/20 | 0.56 |
| ▸ | CA12 | O43570 | 1/20 | 0.53 |
| ▸ | CA1 | P00915 | 1/20 | 0.53 |
| ▸ | CA2 | P00918 | 1/20 | 0.53 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL11871745 | 0.87 | MTOR (0.58) | MAPTKMT2AMEN1HTTRAB9A | |
| SCHEMBL11872659 | 0.87 | LMNA (0.56) | MAPTKMT2AMEN1HTTRAB9A | |
| SCHEMBL11873631 | 0.86 | LMNA (0.67) | MAPTKMT2AMEN1HTTRAB9A | |
| SCHEMBL11861094 | 0.86 | NPC1 (0.61) | MAPTKMT2AMEN1HTTRAB9A | |
| SCHEMBL11875075 | 0.85 | NPC1 (0.62) | MAPTKMT2AMEN1HTTRAB9A | |
| SCHEMBL11870259 | 0.84 | EPHX2 (0.63) | MAPTKMT2AMEN1HTTRAB9A | |
| SCHEMBL11868819 | 0.83 | DYRK1A (0.64) | MAPTKMT2AMEN1HTTRAB9A | |
| SCHEMBL11859503 | 0.82 | KMT2A (0.61) | MAPTKMT2AMEN1HTTLMNA | |
| SCHEMBL12204412 | 0.82 | NCOA1 (0.64) | MAPTKMT2AMEN1HTTRAB9A | |
| SCHEMBL5597699 | 0.82 | KMT2A (0.90) | MAPTKMT2AMEN1HTTRAB9A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-3990879-A | SUBSTITUTED 1-THIADIAZOLYL-3-ARYL-UREAS | ELI LILLY AND COMPANY (US) | 1976-11-09 | — | — | US | disclosed |