Predicted protein targets (top 10)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PTGER2 | P43116 | 7/20 | 0.44 |
| ▸ | PTGER4 | P35408 | 4/20 | 0.44 |
| ▸ | PTGER3 | P43115 | 4/20 | 0.44 |
| ▸ | MEN1 | O00255 | 1/20 | 0.40 |
| ▸ | GALR3 | O60755 | 1/20 | 0.40 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.40 |
| ▸ | POLB | P06746 | 1/20 | 0.40 |
| ▸ | POLA1 | P09884 | 1/20 | 0.40 |
| ▸ | MMP1 | P03956 | 2/20 | 0.34 |
| ▸ | MMP3 | P08254 | 2/20 | 0.34 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL11863937 | 1.00 | PTGER2 (0.44) | PTGER2PTGER4PTGER3MEN1GALR3 | |
| SCHEMBL11863946 | 1.00 | PTGER2 (0.44) | PTGER2PTGER4PTGER3MEN1GALR3 | |
| SCHEMBL11866427 | 0.86 | MEN1 (0.52) | PTGER2PTGER4PTGER3MEN1GALR3 | |
| SCHEMBL11866433 | 0.86 | MEN1 (0.52) | PTGER2PTGER4PTGER3MEN1GALR3 | |
| SCHEMBL11866423 | 0.86 | MEN1 (0.52) | PTGER2PTGER4PTGER3MEN1GALR3 | |
| SCHEMBL11865876 | 0.85 | PTGER2 (0.53) | PTGER2PTGER4PTGER3MEN1GALR3 | |
| SCHEMBL11865889 | 0.85 | PTGER2 (0.53) | PTGER2PTGER4PTGER3MEN1GALR3 | |
| SCHEMBL11865880 | 0.85 | PTGER2 (0.53) | PTGER2PTGER4PTGER3MEN1GALR3 | |
| SCHEMBL11719721 | 0.84 | PTGER2 (0.55) | PTGER2PTGER4PTGER3MEN1GALR3 | |
| SCHEMBL11863443 | 0.81 | LMNA (0.50) | PTGER2PTGER4PTGER3MEN1KMT2A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-3984455-A | Prostaglandin E1 analogs | THE UPJOHN COMPANY (US) | 1976-10-05 | — | — | US | disclosed |