Predicted protein targets (top 15)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TRPA1 | O75762 | 2/20 | 0.48 |
| ▸ | NR4A2 | P43354 | 2/20 | 0.48 |
| ▸ | PTGER2 | P43116 | 7/20 | 0.48 |
| ▸ | PTGER3 | P43115 | 2/20 | 0.48 |
| ▸ | PTGER4 | P35408 | 1/20 | 0.48 |
| ▸ | DNTT | P04053 | 1/20 | 0.46 |
| ▸ | PPARG | P37231 | 4/20 | 0.44 |
| ▸ | PPARA | Q07869 | 2/20 | 0.44 |
| ▸ | PPARD | Q03181 | 1/20 | 0.44 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.40 |
| ▸ | DAGLA | Q9Y4D2 | 1/20 | 0.39 |
| ▸ | TBXA2R | P21731 | 1/20 | 0.38 |
| ▸ | PTGFR | P43088 | 1/20 | 0.38 |
| ▸ | FFAR4 | Q5NUL3 | 1/20 | 0.38 |
| ▸ | FFAR1 | O14842 | 1/20 | 0.38 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL11866497 | 1.00 | TRPA1 (0.48) | TRPA1NR4A2PTGER2PTGER3PTGER4 | |
| SCHEMBL11867713 | 0.89 | TRPA1 (0.49) | TRPA1NR4A2PTGER2PTGER3PTGER4 | |
| SCHEMBL11867721 | 0.89 | TRPA1 (0.49) | TRPA1NR4A2PTGER2PTGER3PTGER4 | |
| SCHEMBL10704086 | 0.85 | DNTT (0.44) | TRPA1NR4A2PTGER2PTGER3PTGER4 | |
| SCHEMBL11867811 | 0.85 | DNTT (0.42) | TRPA1NR4A2PTGER2PTGER3PTGER4 | |
| SCHEMBL11867800 | 0.85 | DNTT (0.42) | TRPA1NR4A2PTGER2PTGER3PTGER4 | |
| SCHEMBL11866493 | 0.84 | DNTT (0.50) | TRPA1NR4A2PTGER2PTGER3PTGER4 | |
| SCHEMBL11866489 | 0.84 | DNTT (0.50) | TRPA1NR4A2PTGER2PTGER3PTGER4 | |
| SCHEMBL11869689 | 0.83 | TRPA1 (0.42) | TRPA1NR4A2PTGER2PTGER3PTGER4 | |
| SCHEMBL11869680 | 0.83 | TRPA1 (0.42) | TRPA1NR4A2PTGER2PTGER3PTGER4 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-3984455-A | Prostaglandin E1 analogs | THE UPJOHN COMPANY (US) | 1976-10-05 | — | — | US | disclosed |