Predicted protein targets (top 7)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | RAD52 | P43351 | 1/20 | 0.76 |
| ▸ | IKBKB | O14920 | 4/20 | 0.46 |
| ▸ | CNR2 | P34972 | 9/20 | 0.46 |
| ▸ | CNR1 | P21554 | 3/20 | 0.46 |
| ▸ | POLB | P06746 | 1/20 | 0.42 |
| ▸ | MDM4 | O15151 | 1/20 | 0.42 |
| ▸ | MDM2 | Q00987 | 1/20 | 0.42 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL11859430 | 0.91 | RAD52 (0.75) | RAD52CNR2CNR1 | |
| Hydrochloric Acid SCHEMBL11854978 | 0.90 | RAD52 (0.74) | RAD52CNR2CNR1 | |
| SCHEMBL11856379 | 0.90 | RAD52 (0.90) | RAD52CNR2CNR1 | |
| Iodomethane SCHEMBL11870131 | 0.90 | RAD52 (0.73) | RAD52CNR2CNR1 | |
| SCHEMBL32690250 | 0.86 | RAD52 (1.00) | RAD52 | |
| Hydrochloric Acid SCHEMBL11866779 | 0.85 | RAD52 (0.98) | RAD52 | |
| Hydrochloric Acid SCHEMBL11867166 | 0.85 | RAD52 (0.74) | RAD52POLB | |
| Hydrochloric Acid SCHEMBL11864998 | 0.84 | RAD52 (0.57) | RAD52IKBKBCNR2CNR1 | |
| SCHEMBL11867074 | 0.82 | RAD52 (0.62) | RAD52IKBKBCNR2CNR1 | |
| SCHEMBL11865957 | 0.80 | RAD52 (0.53) | RAD52IKBKBCNR2CNR1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-3940418-A | Esters and amides of 4,5-dihydrobenz[g]indazole-3-carboxylic acids and related compounds | G. D. SEARLE & CO. (US) | 1976-02-24 | — | — | US | disclosed |