Predicted protein targets (top 10)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | RAD52 | P43351 | 1/20 | 0.62 |
| ▸ | CNR2 | P34972 | 9/20 | 0.49 |
| ▸ | CNR1 | P21554 | 3/20 | 0.49 |
| ▸ | NFKB1 | P19838 | 1/20 | 0.47 |
| ▸ | NFKB2 | Q00653 | 1/20 | 0.47 |
| ▸ | RELA | Q04206 | 1/20 | 0.47 |
| ▸ | MALT1 | Q9UDY8 | 1/20 | 0.47 |
| ▸ | IKBKB | O14920 | 1/20 | 0.45 |
| ▸ | MAPT | P10636 | 1/20 | 0.43 |
| ▸ | THRB | P10828 | 1/20 | 0.43 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL11860266 | 0.94 | RAD52 (0.58) | RAD52CNR2CNR1NFKB1NFKB2 | |
| SCHEMBL11859430 | 0.91 | RAD52 (0.75) | RAD52CNR2CNR1MAPT | |
| SCHEMBL11863032 | 0.90 | RAD52 (0.62) | RAD52CNR2CNR1 | |
| Hydrochloric Acid SCHEMBL11854978 | 0.90 | RAD52 (0.74) | RAD52CNR2CNR1MAPT | |
| Iodomethane SCHEMBL11870131 | 0.89 | RAD52 (0.73) | RAD52CNR2CNR1MAPT | |
| SCHEMBL11859404 | 0.85 | RAD52 (0.54) | RAD52CNR2CNR1 | |
| SCHEMBL11870710 | 0.84 | CNR2 (0.54) | RAD52CNR2CNR1 | |
| SCHEMBL11858506 | 0.83 | CNR2 (0.56) | RAD52CNR2CNR1 | |
| SCHEMBL11859533 | 0.83 | RAD52 (0.47) | RAD52CNR2CNR1IKBKB | |
| SCHEMBL11863304 | 0.82 | ABCB1 (0.59) | RAD52CNR2CNR1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-3940418-A | Esters and amides of 4,5-dihydrobenz[g]indazole-3-carboxylic acids and related compounds | G. D. SEARLE & CO. (US) | 1976-02-24 | — | — | US | disclosed |