Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TBK1 | Q9UHD2 | 10/20 | 0.53 |
| ▸ | IKBKE | Q14164 | 5/20 | 0.50 |
| ▸ | NPC1 | O15118 | 5/20 | 0.50 |
| ▸ | RAB9A | P51151 | 5/20 | 0.50 |
| ▸ | KDM4E | B2RXH2 | 3/20 | 0.50 |
| ▸ | PKM | P14618 | 2/20 | 0.50 |
| ▸ | ADRA1A | P35348 | 2/20 | 0.50 |
| ▸ | ABCC4 | O15439 | 1/20 | 0.50 |
| ▸ | TTR | P02766 | 1/20 | 0.50 |
| ▸ | GAA | P10253 | 1/20 | 0.50 |
| ▸ | OPRD1 | P41143 | 1/20 | 0.50 |
| ▸ | PDE4D | Q08499 | 1/20 | 0.50 |
| ▸ | PDE3A | Q14432 | 1/20 | 0.50 |
| ▸ | GPR35 | Q9HC97 | 1/20 | 0.50 |
| ▸ | AKR1B1 | P15121 | 1/20 | 0.45 |
| ▸ | PTGS2 | P35354 | 3/20 | 0.43 |
| ▸ | PTGS1 | P23219 | 2/20 | 0.43 |
| ▸ | AKR1C3 | P42330 | 2/20 | 0.43 |
| ▸ | AKR1C2 | P52895 | 2/20 | 0.43 |
| ▸ | CDC42 | P60953 | 1/20 | 0.43 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL11860618 | 0.85 | TBK1 (0.56) | TBK1IKBKENPC1RAB9AKDM4E | |
| SCHEMBL11815286 | 0.79 | NPC1 (0.54) | TBK1IKBKENPC1RAB9AKDM4E | |
| SCHEMBL11861723 | 0.78 | KDM4E (0.55) | TBK1IKBKENPC1RAB9AKDM4E | |
| SCHEMBL30679578 | 0.78 | KDM4E (0.55) | TBK1IKBKENPC1RAB9AKDM4E | |
| SCHEMBL11067358 | 0.74 | TTR (0.58) | TBK1NPC1RAB9AKDM4ETTR | |
| SCHEMBL29539979 | 0.74 | TTR (0.58) | TBK1NPC1RAB9AKDM4ETTR | |
| SCHEMBL10990089 | 0.73 | TBK1 (0.61) | TBK1IKBKENPC1RAB9AKDM4E | |
| SCHEMBL11824420 | 0.71 | KDM4E (0.55) | TBK1IKBKENPC1RAB9AKDM4E | |
| SCHEMBL24823412 | 0.70 | KDM4E (0.51) | TBK1IKBKENPC1RAB9AKDM4E | |
| SCHEMBL31151880 | 0.70 | KDM4E (0.51) | TBK1IKBKENPC1RAB9AKDM4E |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-3931205-A | ANTIRHEUMATIC, ANTIINFLAMMATORY, ANALGESIC, ANTIPYRETIC | YOSHITOMI PHARMACEUTICAL INDUSTRIES, LTD. (JA) | 1976-01-06 | — | — | US | disclosed |