Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TRPA1 | O75762 | 4/20 | 0.57 |
| ▸ | NR4A2 | P43354 | 3/20 | 0.57 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.42 |
| ▸ | ALOX15 | P16050 | 2/20 | 0.42 |
| ▸ | TDP1 | Q9NUW8 | 2/20 | 0.42 |
| ▸ | USP2 | O75604 | 1/20 | 0.42 |
| ▸ | PPARG | P37231 | 2/20 | 0.40 |
| ▸ | MEN1 | O00255 | 2/20 | 0.40 |
| ▸ | LMNA | P02545 | 2/20 | 0.40 |
| ▸ | HPGD | P15428 | 2/20 | 0.40 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.40 |
| ▸ | HIF1A | Q16665 | 2/20 | 0.40 |
| ▸ | POLB | P06746 | 1/20 | 0.40 |
| ▸ | NR4A1 | P22736 | 1/20 | 0.40 |
| ▸ | PTPN7 | P35236 | 1/20 | 0.40 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.40 |
| ▸ | PPARD | Q03181 | 1/20 | 0.40 |
| ▸ | PPARA | Q07869 | 1/20 | 0.40 |
| ▸ | TSHR | P16473 | 3/20 | 0.37 |
| ▸ | CYP3A4 | P08684 | 2/20 | 0.37 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL11868668 | 1.00 | TRPA1 (0.57) | TRPA1NR4A2ALDH1A1ALOX15TDP1 | |
| SCHEMBL11868659 | 1.00 | TRPA1 (0.57) | TRPA1NR4A2ALDH1A1ALOX15TDP1 | |
| SCHEMBL11868889 | 0.87 | TRPA1 (0.77) | TRPA1NR4A2ALDH1A1PPARGMEN1 | |
| SCHEMBL14577827 | 0.87 | TRPA1 (0.77) | TRPA1NR4A2ALDH1A1PPARGMEN1 | |
| SCHEMBL11868897 | 0.87 | TRPA1 (0.77) | TRPA1NR4A2ALDH1A1PPARGMEN1 | |
| SCHEMBL11868893 | 0.87 | TRPA1 (0.77) | TRPA1NR4A2ALDH1A1PPARGMEN1 | |
| SCHEMBL11863887 | 0.85 | TRPA1 (0.50) | TRPA1NR4A2ALDH1A1ALOX15TDP1 | |
| SCHEMBL11863884 | 0.85 | TRPA1 (0.50) | TRPA1NR4A2ALDH1A1ALOX15TDP1 | |
| SCHEMBL11863889 | 0.85 | TRPA1 (0.50) | TRPA1NR4A2ALDH1A1ALOX15TDP1 | |
| SCHEMBL11871423 | 0.82 | TRPA1 (0.55) | TRPA1NR4A2ALDH1A1ALOX15TDP1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-3984455-A | Prostaglandin E1 analogs | THE UPJOHN COMPANY (US) | 1976-10-05 | — | — | US | disclosed |