Predicted protein targets (top 12)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PDPK1 | O15530 | 1/20 | 0.38 |
| ▸ | DAPK3 | O43293 | 1/20 | 0.32 |
| ▸ | CSNK1A1 | P48729 | 1/20 | 0.32 |
| ▸ | LIMK1 | P53667 | 1/20 | 0.32 |
| ▸ | TNK2 | Q07912 | 1/20 | 0.32 |
| ▸ | ROCK1 | Q13464 | 1/20 | 0.32 |
| ▸ | CLK4 | Q9HAZ1 | 1/20 | 0.32 |
| ▸ | DYRK1B | Q9Y463 | 1/20 | 0.32 |
| ▸ | MAP2K3 | P46734 | 2/20 | 0.31 |
| ▸ | IKBKB | O14920 | 3/20 | 0.30 |
| ▸ | F2 | P00734 | 1/20 | 0.30 |
| ▸ | HSP90AB1 | P08238 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL27886757 | 0.77 | PDPK1 (0.40) | PDPK1MAP2K3IKBKBF2 | |
| SCHEMBL26684112 | 0.74 | PDPK1 (0.38) | PDPK1MAP2K3IKBKBF2HSP90AB1 | |
| SCHEMBL12661719 | 0.74 | PDPK1 (0.38) | PDPK1DAPK3CSNK1A1LIMK1TNK2 | |
| SCHEMBL7264803 | 0.71 | EEF2K (0.30) | — | |
| SCHEMBL1477709 | 0.70 | CCNA2 (0.41) | PDPK1DAPK3CSNK1A1LIMK1TNK2 | |
| SCHEMBL13460071 | 0.69 | PDPK1 (0.38) | PDPK1IKBKBF2HSP90AB1 | |
| SCHEMBL18337153 | 0.69 | LMNA (0.41) | PDPK1LIMK1IKBKB | |
| SCHEMBL6570704 | 0.68 | PDPK1 (0.33) | PDPK1IKBKB | |
| SCHEMBL13460095 | 0.67 | IKBKB (0.38) | PDPK1IKBKB | |
| SCHEMBL27957609 | 0.67 | PDPK1 (0.36) | PDPK1F2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2024077391-A1 | THIAZOLO[5,4-D]PYRIMIDINE COMPOUNDS, COMPOSITIONS COMPRISING THEM AND USES THEREOF | UNIVERSITE DE MONTREAL (CA) | 2024-04-18 | — | — | WO | disclosed |
| CN-103709119-B | Preparation method of 5-aminothiazole-4-formamide | SHANGHAI INST TECHNOLOGY | 2015-05-20 | — | — | CN | disclosed |
| CN-103709119-A | Preparation method of 5-aminothiazole-4-formamide | SHANGHAI INST TECHNOLOGY | 2014-04-09 | — | — | CN | disclosed |
| US-3993661-A | Quinone methide photograhpic reagent precursors | POLAROID CORPORATION (US) | 1976-11-23 | — | — | US | disclosed |