Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 5/20 | 0.60 |
| ▸ | PPARG | P37231 | 5/20 | 0.60 |
| ▸ | F7 | P08709 | 4/20 | 0.60 |
| ▸ | F3 | P13726 | 4/20 | 0.60 |
| ▸ | PPARD | Q03181 | 4/20 | 0.60 |
| ▸ | PPARA | Q07869 | 4/20 | 0.60 |
| ▸ | KDM4E | B2RXH2 | 4/20 | 0.60 |
| ▸ | FFAR1 | O14842 | 3/20 | 0.60 |
| ▸ | LMNA | P02545 | 2/20 | 0.60 |
| ▸ | CYP3A4 | P08684 | 2/20 | 0.60 |
| ▸ | CYP19A1 | P11511 | 2/20 | 0.60 |
| ▸ | FABP4 | P15090 | 2/20 | 0.60 |
| ▸ | HPGD | P15428 | 2/20 | 0.60 |
| ▸ | ALOX15 | P16050 | 2/20 | 0.60 |
| ▸ | PTGS1 | P23219 | 2/20 | 0.60 |
| ▸ | AKR1C3 | P42330 | 2/20 | 0.60 |
| ▸ | NR4A2 | P43354 | 2/20 | 0.60 |
| ▸ | HSD17B10 | Q99714 | 2/20 | 0.60 |
| ▸ | TDP1 | Q9NUW8 | 2/20 | 0.60 |
| ▸ | DUSP3 | P51452 | 1/20 | 0.60 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL11861396 | 1.00 | ALDH1A1 (0.60) | ALDH1A1PPARGF7F3PPARD | |
| SCHEMBL1331618 | 1.00 | ALDH1A1 (0.60) | ALDH1A1PPARGF7F3PPARD | |
| SCHEMBL11861390 | 1.00 | ALDH1A1 (0.60) | ALDH1A1PPARGF7F3PPARD | |
| SCHEMBL17629191 | 1.00 | ALDH1A1 (0.60) | ALDH1A1PPARGF7F3PPARD | |
| SCHEMBL28502905 | 1.00 | ALDH1A1 (0.60) | ALDH1A1PPARGF7F3PPARD | |
| SCHEMBL10481473 | 0.98 | PPARG (0.59) | ALDH1A1PPARGF7F3PPARD | |
| SCHEMBL10481472 | 0.98 | PPARG (0.59) | ALDH1A1PPARGF7F3PPARD | |
| SCHEMBL8659606 | 0.97 | ALDH1A1 (0.56) | ALDH1A1PPARGF7F3PPARD | |
| SCHEMBL8659602 | 0.97 | ALDH1A1 (0.56) | ALDH1A1PPARGF7F3PPARD | |
| SCHEMBL1370453 | 0.95 | PPARG (0.59) | ALDH1A1PPARGF7F3PPARD |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-117838820-A | Traditional Chinese medicine composition for treating cancer-induced fatigue as well as preparation and application thereof | 中国中医科学院望京医院(中国中医科学院骨伤科研究所) | 2024-04-09 | — | — | CN | disclosed |
| US-3972907-A | Anti-hyperlipidemic fatty acids and esters | G. D. SEARLE & CO. (US) | 1976-08-03 | — | — | US | disclosed |