Predicted protein targets (top 9)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ITGB2 | P05107 | 14/20 | 0.80 |
| ▸ | ICAM1 | P05362 | 14/20 | 0.80 |
| ▸ | ITGAL | P20701 | 14/20 | 0.80 |
| ▸ | BBOX1 | O75936 | 2/20 | 0.64 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.63 |
| ▸ | POLB | P06746 | 1/20 | 0.63 |
| ▸ | MAPT | P10636 | 1/20 | 0.63 |
| ▸ | HPGD | P15428 | 1/20 | 0.63 |
| ▸ | ERAP2 | Q6P179 | 1/20 | 0.63 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL11868630 | 1.00 | ITGB2 (0.80) | ITGB2ICAM1ITGALBBOX1ALDH1A1 | |
| SCHEMBL11869919 | 1.00 | ITGB2 (0.80) | ITGB2ICAM1ITGALBBOX1ALDH1A1 | |
| SCHEMBL16834384 | 0.88 | ITGB2 (0.74) | ITGB2ICAM1ITGALBBOX1ALDH1A1 | |
| SCHEMBL30081478 | 0.88 | ITGB2 (0.74) | ITGB2ICAM1ITGALALDH1A1POLB | |
| SCHEMBL1358036 | 0.86 | ITGB2 (0.80) | ITGB2ICAM1ITGALALDH1A1POLB | |
| SCHEMBL15145360 | 0.86 | ITGB2 (0.74) | ITGB2ICAM1ITGALBBOX1ALDH1A1 | |
| SCHEMBL15780958 | 0.86 | ITGB2 (0.79) | ITGB2ICAM1ITGALALDH1A1POLB | |
| SCHEMBL12063160 | 0.86 | ITGB2 (0.71) | ITGB2ICAM1ITGALALDH1A1POLB | |
| SCHEMBL1358031 | 0.86 | ITGB2 (0.80) | ITGB2ICAM1ITGALALDH1A1POLB | |
| SCHEMBL11949519 | 0.86 | ITGB2 (0.85) | ITGB2ICAM1ITGALALDH1A1POLB |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-114026106-A | Abiraterone prodrugs | 普洛拉治疗公司 | 2022-02-08 | — | — | CN | disclosed |
| CN-106687457-B | Heteroaryl compounds for kinase inhibition | 阿里亚德医药股份有限公司 | 2020-01-10 | — | — | CN | disclosed |
| US-4000297-A | GASTROENTERIC ACTIVITY | ROTTA RESEARCH LABORATORIUM S.P.A. (IT) | 1976-12-28 | — | — | US | disclosed |