Predicted protein targets (top 14)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.68 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.68 |
| ▸ | KCNK3 | O14649 | 1/20 | 0.68 |
| ▸ | THRB | P10828 | 1/20 | 0.68 |
| ▸ | CNR2 | P34972 | 1/20 | 0.68 |
| ▸ | BLM | P54132 | 1/20 | 0.68 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.68 |
| ▸ | SLC6A5 | Q9Y345 | 1/20 | 0.68 |
| ▸ | ASAH2 | Q9NR71 | 1/20 | 0.63 |
| ▸ | MEN1 | O00255 | 1/20 | 0.62 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.62 |
| ▸ | CNR1 | P21554 | 2/20 | 0.61 |
| ▸ | HPGD | P15428 | 1/20 | 0.61 |
| ▸ | TRPV1 | Q8NER1 | 1/20 | 0.61 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL653624 | 1.00 | ALDH1A1 (0.68) | ALDH1A1SMN1; SMN2KCNK3THRBCNR2 | |
| SCHEMBL5682652 | 1.00 | ALDH1A1 (0.68) | ALDH1A1SMN1; SMN2KCNK3THRBCNR2 | |
| SCHEMBL5145799 | 1.00 | ALDH1A1 (0.68) | ALDH1A1SMN1; SMN2KCNK3THRBCNR2 | |
| SCHEMBL375483 | 0.95 | CNR2 (0.74) | ALDH1A1SMN1; SMN2KCNK3THRBCNR2 | |
| SCHEMBL5889532 | 0.95 | CNR2 (0.74) | ALDH1A1SMN1; SMN2KCNK3THRBCNR2 | |
| SCHEMBL9109309 | 0.95 | ASAH2 (0.68) | ALDH1A1SMN1; SMN2KCNK3THRBCNR2 | |
| SCHEMBL6846748 | 0.95 | ASAH2 (0.68) | ALDH1A1SMN1; SMN2KCNK3THRBCNR2 | |
| SCHEMBL1147692 | 0.95 | ASAH2 (0.68) | ALDH1A1SMN1; SMN2KCNK3THRBCNR2 | |
| SCHEMBL2225404 | 0.95 | ASAH2 (0.68) | ALDH1A1SMN1; SMN2KCNK3THRBCNR2 | |
| SCHEMBL11867138 | 0.91 | ALDH1A1 (0.59) | ALDH1A1SMN1; SMN2KCNK3THRBCNR2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-3985875-A | RENIN INHIBITION, ANTIHYPERTENSIVE, ANTICHOLESTEROL AGENTS | DAINIPPON PHARMACEUTICAL CO., LTD. (JA) | 1976-10-12 | — | — | US | disclosed |