SCHEMBL11873136

SCHEMBL11873136

C=CCOC(=O)C=C(C=Cc1ccccc1)C(=O)OCC=C

nearest known ligand 0.50

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
APP P05067 1/20 0.50
CASP1 P29466 1/20 0.49
LMNA P02545 3/20 0.49
AKR1B10 O60218 2/20 0.47
AKR1B1 P15121 2/20 0.47
CYP3A4 P08684 1/20 0.46
MAPT P10636 4/20 0.44
MEN1 O00255 3/20 0.43
KMT2A Q03164 3/20 0.43
MAPK1 P28482 2/20 0.43
KDM4E B2RXH2 1/20 0.43
GAA P10253 1/20 0.43
CA12 O43570 1/20 0.43
CA4 P22748 1/20 0.43
CA6 P23280 1/20 0.43
CA5A P35218 1/20 0.43
CA7 P43166 1/20 0.43
CA9 Q16790 1/20 0.43
CA14 Q9ULX7 1/20 0.43
CA5B Q9Y2D0 1/20 0.43

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
Allyl Cinnamate SCHEMBL30689543 0.87 APP (0.63) APPCASP1LMNAAKR1B10AKR1B1
Allyl Cinnamate SCHEMBL45457 0.87 APP (0.63) APPCASP1LMNAAKR1B10AKR1B1
Allyl Cinnamate SCHEMBL45456 0.87 APP (0.63) APPCASP1LMNAAKR1B10AKR1B1
Allyl Cinnamate SCHEMBL15657439 0.82 APP (0.52) APPCASP1LMNAAKR1B10AKR1B1
Allyl Cinnamate SCHEMBL28223748 0.82 CYP3A4 (0.69) APPCASP1LMNAAKR1B10AKR1B1
Allyl Cinnamate SCHEMBL28223749 0.82 CYP3A4 (0.69) APPCASP1LMNAAKR1B10AKR1B1
SCHEMBL9716477 0.81 HDAC3 (0.46) APPCASP1LMNAAKR1B10AKR1B1
SCHEMBL4928343 0.81 MAPT (0.61) APPCASP1LMNAAKR1B10AKR1B1
SCHEMBL4928347 0.81 MAPT (0.61) APPCASP1LMNAAKR1B10AKR1B1
SCHEMBL28033880 0.80 CA12 (0.55) LMNAAKR1B10AKR1B1CYP3A4MAPT

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-3970362-A Process of producing polarizing optical devices and product thereof AMERICAN OPTICAL CORPORATION (US) 1976-07-20 US claimed