Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HDAC3 | O15379 | 1/20 | 0.46 |
| ▸ | TNKS | O95271 | 1/20 | 0.46 |
| ▸ | HDAC4 | P56524 | 1/20 | 0.46 |
| ▸ | HDAC1 | Q13547 | 1/20 | 0.46 |
| ▸ | HCAR2 | Q8TDS4 | 1/20 | 0.46 |
| ▸ | HDAC7 | Q8WUI4 | 1/20 | 0.46 |
| ▸ | HDAC2 | Q92769 | 1/20 | 0.46 |
| ▸ | HDAC10 | Q969S8 | 1/20 | 0.46 |
| ▸ | HDAC11 | Q96DB2 | 1/20 | 0.46 |
| ▸ | HDAC8 | Q9BY41 | 1/20 | 0.46 |
| ▸ | TNKS2 | Q9H2K2 | 1/20 | 0.46 |
| ▸ | HDAC6 | Q9UBN7 | 1/20 | 0.46 |
| ▸ | HDAC9 | Q9UKV0 | 1/20 | 0.46 |
| ▸ | HDAC5 | Q9UQL6 | 1/20 | 0.46 |
| ▸ | CASP1 | P29466 | 1/20 | 0.45 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.44 |
| ▸ | LMNA | P02545 | 3/20 | 0.43 |
| ▸ | MAPT | P10636 | 5/20 | 0.42 |
| ▸ | APP | P05067 | 1/20 | 0.42 |
| ▸ | MEN1 | O00255 | 3/20 | 0.42 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL4559229 | 0.85 | CASP1 (0.44) | CASP1CYP3A4LMNAMAPTAPP | |
| SCHEMBL11004796 | 0.84 | CYP3A4 (0.44) | CASP1CYP3A4LMNAMAPTAPP | |
| SCHEMBL2411758 | 0.84 | MEN1 (0.51) | HDAC3TNKSHDAC4HDAC1HCAR2 | |
| Styrene SCHEMBL327788 | 0.82 | CYP3A4 (0.38) | HCAR2CASP1CYP3A4LMNAMAPT | |
| SCHEMBL11873136 | 0.81 | APP (0.50) | HDAC3TNKSHDAC4HDAC1HCAR2 | |
| SCHEMBL9547843 | 0.80 | CASP1 (0.42) | CASP1CYP3A4LMNAMAPTAPP | |
| SCHEMBL1234803 | 0.80 | KDM4E (0.54) | HDAC3TNKSHDAC4HDAC1HCAR2 | |
| SCHEMBL8047206 | 0.79 | HDAC3 (0.53) | HDAC3TNKSHDAC4HDAC1HCAR2 | |
| SCHEMBL4928343 | 0.79 | MAPT (0.61) | HDAC3TNKSHDAC4HDAC1HCAR2 | |
| SCHEMBL4928347 | 0.79 | MAPT (0.61) | HDAC3TNKSHDAC4HDAC1HCAR2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5110874-A | Polyamine salt of polymer of styrene and alkyl acrylate having some carboxylic acid groups | PETROLITE CORPORATION (US) | 1992-05-05 | — | — | US | disclosed |
| US-4983186-A | ADDING OIL SOLUBLE POLYAMINE AND TERPOLYMER OF STYRENE, ALKYL ACRYLATE AND (METH)ACRYLIC ACID | PETROLITE CORPORATION (US) | 1991-01-08 | — | — | US | disclosed |