Predicted protein targets (top 11)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CA1 | P00915 | 5/20 | 0.47 |
| ▸ | CA2 | P00918 | 5/20 | 0.47 |
| ▸ | CA9 | Q16790 | 5/20 | 0.47 |
| ▸ | CA12 | O43570 | 4/20 | 0.47 |
| ▸ | PTK2 | Q05397 | 4/20 | 0.46 |
| ▸ | EGFR | P00533 | 4/20 | 0.45 |
| ▸ | ERBB2 | P04626 | 4/20 | 0.45 |
| ▸ | TERT | O14746 | 1/20 | 0.40 |
| ▸ | GLA | P06280 | 1/20 | 0.38 |
| ▸ | LMNA | P02545 | 1/20 | 0.38 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.38 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL11873312 | 1.00 | CA1 (0.47) | CA1CA2CA9CA12PTK2 | |
| SCHEMBL11868510 | 0.85 | CA1 (0.50) | CA1CA2CA9CA12PTK2 | |
| SCHEMBL11868504 | 0.85 | CA1 (0.50) | CA1CA2CA9CA12PTK2 | |
| SCHEMBL9232636 | 0.82 | CA1 (0.70) | CA1CA2CA9CA12EGFR | |
| SCHEMBL11860800 | 0.79 | CA1 (0.53) | CA1CA2CA9CA12EGFR | |
| SCHEMBL11863480 | 0.77 | GLA (0.50) | PTK2EGFRERBB2TERTGLA | |
| SCHEMBL11863488 | 0.77 | GLA (0.50) | PTK2EGFRERBB2TERTGLA | |
| SCHEMBL11863880 | 0.76 | LMNA (0.42) | CA1CA2CA9CA12PTK2 | |
| SCHEMBL11861038 | 0.76 | LMNA (0.42) | CA1CA2CA9CA12PTK2 | |
| SCHEMBL11859914 | 0.76 | MAPK1 (0.58) | CA1CA2CA9CA12EGFR |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-3952007-A | Processes for preparing 5-nitro-1-methyl-2-(2-dialkylaminovinyl)-imidazole and 5-nitro-1-methyl-2-imidazolyl carboxaldehyde | SCHERING AKTIENGESELLSCHAFT (DT) | 1976-04-20 | — | — | US | disclosed |