Predicted protein targets (top 14)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MAOB | P27338 | 19/20 | 0.69 |
| ▸ | ADORA2B | P29275 | 3/20 | 0.69 |
| ▸ | MAOA | P21397 | 2/20 | 0.64 |
| ▸ | CA12 | O43570 | 1/20 | 0.61 |
| ▸ | CA1 | P00915 | 1/20 | 0.61 |
| ▸ | CA2 | P00918 | 1/20 | 0.61 |
| ▸ | CA4 | P22748 | 1/20 | 0.61 |
| ▸ | CA5A | P35218 | 1/20 | 0.61 |
| ▸ | CA7 | P43166 | 1/20 | 0.61 |
| ▸ | CA5B | Q9Y2D0 | 1/20 | 0.61 |
| ▸ | NPC1 | O15118 | 1/20 | 0.60 |
| ▸ | MAPT | P10636 | 1/20 | 0.60 |
| ▸ | RAB9A | P51151 | 1/20 | 0.60 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.60 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL4519275 | 0.82 | MAOB (0.72) | MAOBADORA2BMAOA | |
| SCHEMBL30643084 | 0.82 | MAOB (0.72) | MAOBADORA2BMAOANPC1MAPT | |
| SCHEMBL4974849 | 0.82 | MAOB (0.72) | MAOBADORA2BMAOANPC1MAPT | |
| SCHEMBL4973439 | 0.82 | MAOB (1.00) | MAOBADORA2BMAOA | |
| SCHEMBL11875715 | 0.80 | MAOB (0.67) | MAOBADORA2BMAOACA12CA1 | |
| SCHEMBL4972722 | 0.78 | MAOB (1.00) | MAOBADORA2BMAOACA12CA1 | |
| SCHEMBL11877461 | 0.78 | MAOB (0.63) | MAOBADORA2BMAOA | |
| SCHEMBL30059662 | 0.77 | MAOB (1.00) | MAOBADORA2BMAOA | |
| SCHEMBL1253672 | 0.77 | MAOB (1.00) | MAOBADORA2BMAOA | |
| SCHEMBL9029206 | 0.76 | MAOB (0.72) | MAOBADORA2BMAOA |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-3937837-A | SUBSTITUTED CHROMONE-3-CARBONITRILES, CARBOXAMIDES AND CARBOXYLIC ACIDS USEFUL FOR PREVENTING ASTHMATIC SYMPTOMS | WARNER-LAMBERT COMPANY (US) | 1976-02-10 | — | — | US | disclosed |