Predicted protein targets (top 3)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MAOB | P27338 | 20/20 | 1.00 |
| ▸ | ADORA2B | P29275 | 2/20 | 1.00 |
| ▸ | MAOA | P21397 | 1/20 | 0.82 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL4972722 | 0.90 | MAOB (1.00) | MAOBADORA2BMAOA | |
| SCHEMBL4969164 | 0.84 | MAOB (1.00) | MAOBADORA2BMAOA | |
| SCHEMBL5656236 | 0.83 | MAOB (0.70) | MAOBADORA2BMAOA | |
| SCHEMBL31661715 | 0.83 | MAOB (0.70) | MAOBADORA2BMAOA | |
| SCHEMBL11875283 | 0.82 | MAOB (0.69) | MAOBADORA2BMAOA | |
| SCHEMBL30059662 | 0.80 | MAOB (1.00) | MAOBADORA2BMAOA | |
| SCHEMBL1253672 | 0.80 | MAOB (1.00) | MAOBADORA2BMAOA | |
| SCHEMBL11875715 | 0.80 | MAOB (0.67) | MAOBADORA2BMAOA | |
| SCHEMBL4973113 | 0.80 | MAOB (1.00) | MAOBADORA2BMAOA | |
| SCHEMBL4519275 | 0.79 | MAOB (0.72) | MAOBADORA2BMAOA |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 15 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2008104925-A1 | CHROMONE DERIVATIVES FOR USE AS ANTIOXIDANTS/PRESERVATIVES | UNIVERSIDADE DO PORTO (PT) | 2008-09-04 | — | — | WO | claimed |
| US-10391070-B2 | Compositions and methods for treating neurological diseases or injury | MUSC FOUNDATION FOR RESEARCH DEVELOPMENT (US) | 2019-08-27 | — | — | US | disclosed |
| US-10391070-B2 | Compositions and methods for treating neurological diseases or injury | MUSC FOUNDATION FOR RESEARCH DEVELOPMENT (US) | 2019-08-27 | — | — | US | disclosed |
| US-20180185306-A1 | COMPOSITIONS AND METHODS FOR TREATING NEUROLOGICAL DISEASES OR INJURY | MUSC FOUNDATION FOR RESEARCH DEVELOPMENT (US) | 2018-07-05 | — | — | US | disclosed |
| US-20180185306-A1 | COMPOSITIONS AND METHODS FOR TREATING NEUROLOGICAL DISEASES OR INJURY | MUSC FOUNDATION FOR RESEARCH DEVELOPMENT (US) | 2018-07-05 | — | — | US | disclosed |
| US-20180185306-A1 | COMPOSITIONS AND METHODS FOR TREATING NEUROLOGICAL DISEASES OR INJURY | MUSC FOUNDATION FOR RESEARCH DEVELOPMENT (US) | 2018-07-05 | — | — | US | disclosed |
| US-9861596-B2 | Compositions and methods for treating neurological diseases or injury | MUSC FOUNDATION FOR RESEARCH DEVELOPMENT (US) | 2018-01-09 | — | — | US | disclosed |
| US-9861596-B2 | Compositions and methods for treating neurological diseases or injury | MUSC FOUNDATION FOR RESEARCH DEVELOPMENT (US) | 2018-01-09 | — | — | US | disclosed |
| US-20150320702-A1 | COMPOSITIONS AND METHODS FOR TREATING NEUROLOGICAL DISEASES OR INJURY | MEDICAL UNIVERSITY OF SOUTH CAROLINA | 2015-11-12 | — | — | US | disclosed |
| US-20150320702-A1 | COMPOSITIONS AND METHODS FOR TREATING NEUROLOGICAL DISEASES OR INJURY | MEDICAL UNIVERSITY OF SOUTH CAROLINA | 2015-11-12 | — | — | US | disclosed |
| US-20150320702-A1 | COMPOSITIONS AND METHODS FOR TREATING NEUROLOGICAL DISEASES OR INJURY | MEDICAL UNIVERSITY OF SOUTH CAROLINA | 2015-11-12 | — | — | US | disclosed |
| WO-2014074976-A1 | COMPOSITIONS AND METHODS FOR TREATING NEUROLOGICAL DISEASES OR INJURY | MUSC FOUNDATION FOR RESEARCH DEVELOPMENT (US) | 2014-05-15 | — | — | WO | disclosed |
| WO-2014074976-A1 | COMPOSITIONS AND METHODS FOR TREATING NEUROLOGICAL DISEASES OR INJURY | MUSC FOUNDATION FOR RESEARCH DEVELOPMENT (US) | 2014-05-15 | — | — | WO | disclosed |
| WO-2008104925-A1 | CHROMONE DERIVATIVES FOR USE AS ANTIOXIDANTS/PRESERVATIVES | UNIVERSIDADE DO PORTO (PT) | 2008-09-04 | — | — | WO | disclosed |
| US-3937837-A | SUBSTITUTED CHROMONE-3-CARBONITRILES, CARBOXAMIDES AND CARBOXYLIC ACIDS USEFUL FOR PREVENTING ASTHMATIC SYMPTOMS | WARNER-LAMBERT COMPANY (US) | 1976-02-10 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (3 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-10391070-B2 | Compositions and methods for treating neurological diseases or injury | PROC, GLS, NLN | MAOB 1041/4885ADORA2B 822/4885MAOA 1292/4885 |
| US-20150320702-A1 | COMPOSITIONS AND METHODS FOR TREATING NEUROLOGICAL DISEASES OR INJURY | PROC, GLS, NLN | MAOB 1041/4885ADORA2B 822/4885MAOA 1292/4885 |
| US-20180185306-A1 | COMPOSITIONS AND METHODS FOR TREATING NEUROLOGICAL DISEASES OR INJURY | PROC, GLS, NLN | MAOB 1041/4885ADORA2B 822/4885MAOA 1292/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.