Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CA12 | O43570 | 4/20 | 0.68 |
| ▸ | CA2 | P00918 | 4/20 | 0.68 |
| ▸ | CA9 | Q16790 | 3/20 | 0.68 |
| ▸ | MAPT | P10636 | 6/20 | 0.67 |
| ▸ | ALDH1A1 | P00352 | 6/20 | 0.67 |
| ▸ | KDM4E | B2RXH2 | 6/20 | 0.67 |
| ▸ | L3MBTL1 | Q9Y468 | 4/20 | 0.67 |
| ▸ | POLB | P06746 | 4/20 | 0.67 |
| ▸ | MPI | P34949 | 2/20 | 0.67 |
| ▸ | RECQL | P46063 | 1/20 | 0.67 |
| ▸ | ALOX15 | P16050 | 3/20 | 0.55 |
| ▸ | THRB | P10828 | 2/20 | 0.55 |
| ▸ | PKM | P14618 | 2/20 | 0.55 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.55 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.55 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.55 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.55 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.55 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.55 |
| ▸ | HIF1A | Q16665 | 1/20 | 0.55 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL11877164 | 1.00 | CA12 (0.68) | CA12CA2CA9MAPTALDH1A1 | |
| SCHEMBL13051332 | 0.89 | MAPT (0.79) | CA12CA2CA9MAPTALDH1A1 | |
| SCHEMBL1947963 | 0.88 | MAPT (0.78) | CA12CA2CA9MAPTALDH1A1 | |
| SCHEMBL802042 | 0.88 | MAPT (0.78) | CA12CA2CA9MAPTALDH1A1 | |
| SCHEMBL12566830 | 0.88 | MAPT (0.78) | CA12CA2CA9MAPTALDH1A1 | |
| SCHEMBL30970907 | 0.88 | MAPT (0.78) | CA12CA2CA9MAPTALDH1A1 | |
| SCHEMBL802218 | 0.87 | CA12 (0.68) | CA12CA2CA9MAPTALDH1A1 | |
| SCHEMBL3364273 | 0.87 | CA12 (0.68) | CA12CA2CA9MAPTALDH1A1 | |
| SCHEMBL24440665 | 0.86 | CA12 (0.79) | CA12CA2CA9MAPTALDH1A1 | |
| Lithium SCHEMBL3368945 | 0.86 | MAPT (0.76) | CA12CA2CA9MAPTALDH1A1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-3965069-A | Polyphenylene oxide is prepared using a mixture of manganese chelates as a catalyst | GENERAL ELECTRIC COMPANY (US) | 1976-06-22 | — | — | US | disclosed |