Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MAPT | P10636 | 8/20 | 0.79 |
| ▸ | POLB | P06746 | 7/20 | 0.79 |
| ▸ | ALDH1A1 | P00352 | 7/20 | 0.79 |
| ▸ | KDM4E | B2RXH2 | 7/20 | 0.79 |
| ▸ | L3MBTL1 | Q9Y468 | 5/20 | 0.79 |
| ▸ | MPI | P34949 | 3/20 | 0.79 |
| ▸ | RECQL | P46063 | 2/20 | 0.79 |
| ▸ | GAA | P10253 | 7/20 | 0.64 |
| ▸ | HPGD | P15428 | 5/20 | 0.64 |
| ▸ | HSD17B10 | Q99714 | 4/20 | 0.64 |
| ▸ | ALOX15 | P16050 | 4/20 | 0.64 |
| ▸ | ALOX12 | P18054 | 3/20 | 0.64 |
| ▸ | LMNA | P02545 | 3/20 | 0.64 |
| ▸ | THRB | P10828 | 3/20 | 0.64 |
| ▸ | PKM | P14618 | 2/20 | 0.64 |
| ▸ | DHODH | Q02127 | 1/20 | 0.64 |
| ▸ | TSHR | P16473 | 1/20 | 0.64 |
| ▸ | AKR1C3 | P42330 | 1/20 | 0.58 |
| ▸ | AKR1C2 | P52895 | 1/20 | 0.58 |
| ▸ | AKR1C1 | Q04828 | 1/20 | 0.58 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL11877168 | 0.89 | CA12 (0.68) | MAPTPOLBALDH1A1KDM4EL3MBTL1 | |
| SCHEMBL11877164 | 0.89 | CA12 (0.68) | MAPTPOLBALDH1A1KDM4EL3MBTL1 | |
| SCHEMBL30355323 | 0.83 | POLB (0.77) | MAPTPOLBALDH1A1KDM4EL3MBTL1 | |
| SCHEMBL30355322 | 0.83 | POLB (0.77) | MAPTPOLBALDH1A1KDM4EL3MBTL1 | |
| SCHEMBL19974998 | 0.82 | ALDH1A1 (0.77) | MAPTPOLBALDH1A1KDM4EL3MBTL1 | |
| SCHEMBL19975001 | 0.82 | ALDH1A1 (0.77) | MAPTPOLBALDH1A1KDM4EL3MBTL1 | |
| SCHEMBL11409354 | 0.81 | POLB (0.75) | MAPTPOLBALDH1A1KDM4EL3MBTL1 | |
| SCHEMBL11409357 | 0.81 | POLB (0.75) | MAPTPOLBALDH1A1KDM4EL3MBTL1 | |
| SCHEMBL29358114 | 0.81 | POLB (0.75) | MAPTPOLBALDH1A1KDM4EL3MBTL1 | |
| SCHEMBL30139902 | 0.80 | ALDH1A1 (0.73) | MAPTPOLBALDH1A1KDM4EL3MBTL1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20100298559-A1 | OPTICALLY ACTIVE DINICKEL COMPLEX AND METHOD FOR PRODUCING OPTICALLY ACTIVE AMINE USING THE OPTICALLY ACTIVE DINICKEL COMPLEX AS CATALYST | NISSAN CHEMICAL INDUSTRIES, LTD. (JP) | 2010-11-25 | — | — | US | disclosed |
| US-20100298559-A1 | OPTICALLY ACTIVE DINICKEL COMPLEX AND METHOD FOR PRODUCING OPTICALLY ACTIVE AMINE USING THE OPTICALLY ACTIVE DINICKEL COMPLEX AS CATALYST | NISSAN CHEMICAL INDUSTRIES, LTD. (JP) | 2010-11-25 | — | — | US | disclosed |
| EP-2233468-A1 | OPTICALLY ACTIVE DINICKEL COMPLEX AND METHOD FOR PRODUCING OPTICALLY ACTIVE AMINE USING THE OPTICALLY ACTIVE DINICKEL COMPLEX AS CATALYST | Nissan Chemical Industries, Ltd. (JP) | 2010-09-29 | — | — | EP | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20100298559-A1 | OPTICALLY ACTIVE DINICKEL COMPLEX AND METHOD FOR PRODUCING OPTICALLY ACTIVE AMINE USING THE OPTICALLY ACTIVE DINICKEL COMPLEX AS CATALYST | C5, C9, CCNE1 | MAPT 3244/4885POLB 890/4885ALDH1A1 1035/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.