Predicted protein targets (top 17)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KDM4E | B2RXH2 | 8/20 | 0.37 |
| ▸ | ALDH1A1 | P00352 | 5/20 | 0.37 |
| ▸ | TDP1 | Q9NUW8 | 3/20 | 0.37 |
| ▸ | POLB | P06746 | 1/20 | 0.36 |
| ▸ | PKM | P14618 | 1/20 | 0.35 |
| ▸ | SMN1; SMN2 | Q16637 | 3/20 | 0.35 |
| ▸ | TSHR | P16473 | 2/20 | 0.35 |
| ▸ | LMNA | P02545 | 1/20 | 0.35 |
| ▸ | TP53 | P04637 | 1/20 | 0.35 |
| ▸ | MEN1 | O00255 | 3/20 | 0.33 |
| ▸ | KMT2A | Q03164 | 3/20 | 0.33 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.33 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.33 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.33 |
| ▸ | SCN9A | Q15858 | 1/20 | 0.32 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.31 |
| ▸ | GAA | P10253 | 1/20 | 0.31 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL26922256 | 0.86 | KDM4E (0.39) | KDM4EALDH1A1TDP1POLBPKM | |
| SCHEMBL25660483 | 0.82 | KDM4E (0.41) | KDM4EALDH1A1TDP1POLBPKM | |
| SCHEMBL3917900 | 0.82 | KDM4E (0.41) | KDM4EALDH1A1TDP1POLBPKM | |
| SCHEMBL16060209 | 0.79 | ANPEP (0.38) | TDP1 | |
| SCHEMBL11902706 | 0.79 | ANPEP (0.38) | TDP1 | |
| SCHEMBL75595 | 0.79 | ANPEP (0.38) | TDP1 | |
| Hydrochloric Acid SCHEMBL75594 | 0.78 | ANPEP (0.37) | ALDH1A1TDP1 | |
| Hydrochloric Acid SCHEMBL75596 | 0.78 | ANPEP (0.37) | ALDH1A1TDP1 | |
| Hydrochloric Acid SCHEMBL16060207 | 0.78 | ANPEP (0.37) | ALDH1A1TDP1 | |
| SCHEMBL23849174 | 0.76 | METAP2 (0.42) | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-3978034-A | L-Aspartyl dipeptides as sweetening agents | E. R. SQUIBB & SONS, INC. (US) | 1976-08-31 | — | — | US | disclosed |