Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 8/20 | 0.60 |
| ▸ | MAPT | P10636 | 5/20 | 0.60 |
| ▸ | LMNA | P02545 | 3/20 | 0.60 |
| ▸ | SMN1; SMN2 | Q16637 | 3/20 | 0.60 |
| ▸ | ALOX12 | P18054 | 1/20 | 0.60 |
| ▸ | MEN1 | O00255 | 4/20 | 0.58 |
| ▸ | KMT2A | Q03164 | 4/20 | 0.58 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.57 |
| ▸ | L3MBTL1 | Q9Y468 | 2/20 | 0.56 |
| ▸ | TSHR | P16473 | 1/20 | 0.56 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.55 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.55 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.55 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.55 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.53 |
| ▸ | USP2 | O75604 | 1/20 | 0.53 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.53 |
| ▸ | GAA | P10253 | 1/20 | 0.52 |
| ▸ | ESR1 | P03372 | 1/20 | 0.52 |
| ▸ | POLB | P06746 | 2/20 | 0.52 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL11642338 | 0.87 | ALDH1A1 (0.54) | ALDH1A1MAPTLMNASMN1; SMN2ALOX12 | |
| SCHEMBL11744214 | 0.83 | MAPT (0.60) | ALDH1A1MAPTMEN1KMT2AL3MBTL1 | |
| SCHEMBL14557417 | 0.83 | ALDH1A1 (0.49) | ALDH1A1MAPTLMNASMN1; SMN2ALOX12 | |
| SCHEMBL11477922 | 0.82 | MAPT (0.73) | ALDH1A1MAPTLMNASMN1; SMN2ALOX12 | |
| SCHEMBL10675251 | 0.79 | ALDH1A1 (0.65) | ALDH1A1MAPTLMNASMN1; SMN2ALOX12 | |
| SCHEMBL5592639 | 0.79 | ALDH1A1 (0.76) | ALDH1A1MAPTLMNAMEN1KMT2A | |
| SCHEMBL11515264 | 0.78 | ALDH1A1 (0.64) | ALDH1A1MAPTSMN1; SMN2MEN1KMT2A | |
| SCHEMBL14605805 | 0.76 | ALDH1A1 (0.69) | ALDH1A1MAPTLMNASMN1; SMN2ALOX12 | |
| SCHEMBL14605816 | 0.76 | MAPT (0.80) | ALDH1A1MAPTLMNASMN1; SMN2MEN1 | |
| SCHEMBL24210088 | 0.75 | KMT2A (0.83) | ALDH1A1MAPTLMNASMN1; SMN2ALOX12 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-3961959-A | DEVELOPMENT RELEASING INHIBITOR | KONISHIROKU PHOTO INDUSTRY CO., LTD. (JA) | 1976-06-08 | — | — | US | disclosed |