Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ADRB2 | P07550 | 16/20 | 0.60 |
| ▸ | ADRB1 | P08588 | 15/20 | 0.60 |
| ▸ | ADRB3 | P13945 | 16/20 | 0.59 |
| ▸ | ADRA1D | P25100 | 2/20 | 0.57 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.57 |
| ▸ | HTR1A | P08908 | 1/20 | 0.57 |
| ▸ | CHRM5 | P08912 | 1/20 | 0.57 |
| ▸ | DRD2 | P14416 | 1/20 | 0.57 |
| ▸ | ADRA2B | P18089 | 1/20 | 0.57 |
| ▸ | DRD4 | P21917 | 1/20 | 0.57 |
| ▸ | SLC6A2 | P23975 | 1/20 | 0.57 |
| ▸ | FPR3 | P25089 | 1/20 | 0.57 |
| ▸ | HTR1D | P28221 | 1/20 | 0.57 |
| ▸ | HTR1B | P28222 | 1/20 | 0.57 |
| ▸ | HTR2A | P28223 | 1/20 | 0.57 |
| ▸ | HTR2C | P28335 | 1/20 | 0.57 |
| ▸ | SLC6A4 | P31645 | 1/20 | 0.57 |
| ▸ | GPR183 | P32249 | 1/20 | 0.57 |
| ▸ | HTR7 | P34969 | 1/20 | 0.57 |
| ▸ | ADRA1A | P35348 | 1/20 | 0.57 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL11873820 | 0.97 | ADRB2 (0.65) | ADRB2ADRB1ADRB3ADRA1DKDM4E | |
| SCHEMBL11879930 | 0.83 | ADRB2 (0.54) | ADRB2ADRB1ADRB3ADRA1DKDM4E | |
| SCHEMBL11873813 | 0.82 | ADRB2 (0.70) | ADRB2ADRB1ADRB3ADRA1DKDM4E | |
| SCHEMBL11876927 | 0.82 | ADRB2 (0.58) | ADRB2ADRB1ADRB3ADRA1DHTR1A | |
| SCHEMBL10728051 | 0.81 | EPHX2 (0.58) | ADRB2ADRB1ADRB3KDM4E | |
| SCHEMBL10728043 | 0.81 | EPHX2 (0.58) | ADRB2ADRB1ADRB3KDM4E | |
| SCHEMBL10728036 | 0.81 | EPHX2 (0.58) | ADRB2ADRB1ADRB3KDM4E | |
| SCHEMBL11878888 | 0.81 | ADRB3 (0.54) | ADRB2ADRB1ADRB3ADRA1DKDM4E | |
| Hydrochloric Acid SCHEMBL3713557 | 0.81 | ADRB2 (0.70) | ADRB2ADRB1ADRB3ADRA1DKDM4E | |
| SCHEMBL10731030 | 0.79 | KDM4E (0.63) | ADRB2ADRB1ADRB3KDM4EKCNH2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-3943254-A | ALPHA-AMINOMETHYL-4-HYDROXY-3-SULFAMYL BENZYL ALCOHOLS OR 4-HYDROXY-3-SULFAMYL-PHENETHYLAMINE | SMITHKLINE CORPORATION (US) | 1976-03-09 | — | — | US | disclosed |