Predicted protein targets (top 15)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TSHR | P16473 | 3/20 | 0.74 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.74 |
| ▸ | ASAH1 | Q13510 | 7/20 | 0.65 |
| ▸ | GAA | P10253 | 1/20 | 0.46 |
| ▸ | HTT | P42858 | 1/20 | 0.46 |
| ▸ | NPSR1 | Q6W5P4 | 2/20 | 0.46 |
| ▸ | LMNA | P02545 | 2/20 | 0.46 |
| ▸ | TP53 | P04637 | 2/20 | 0.46 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.46 |
| ▸ | MEN1 | O00255 | 2/20 | 0.46 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.46 |
| ▸ | USP2 | O75604 | 1/20 | 0.46 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.46 |
| ▸ | SAE1 | Q9UBE0 | 1/20 | 0.46 |
| ▸ | UBA2 | Q9UBT2 | 1/20 | 0.46 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL6926893 | 0.88 | TSHR (0.79) | TSHRALDH1A1ASAH1GAAHTT | |
| SCHEMBL675169 | 0.88 | TSHR (0.79) | TSHRALDH1A1ASAH1HTTNPSR1 | |
| Benomyl SCHEMBL15681 | 0.85 | TSHR (1.00) | TSHRALDH1A1ASAH1GAAHTT | |
| Benomyl SCHEMBL29379464 | 0.85 | TSHR (1.00) | TSHRALDH1A1ASAH1GAAHTT | |
| Benomyl SCHEMBL8379451 | 0.85 | TSHR (1.00) | TSHRALDH1A1ASAH1GAAHTT | |
| Benomyl SCHEMBL3962065 | 0.84 | TSHR (0.98) | TSHRALDH1A1ASAH1GAAHTT | |
| SCHEMBL7639089 | 0.84 | ASAH1 (0.73) | TSHRALDH1A1ASAH1GAAHTT | |
| SCHEMBL7102687 | 0.83 | TSHR (0.83) | TSHRALDH1A1ASAH1GAAHTT | |
| SCHEMBL11743315 | 0.83 | ASAH1 (0.90) | TSHRALDH1A1ASAH1LMNAKDM4E | |
| Benomyl SCHEMBL28721488 | 0.83 | TSHR (0.94) | TSHRALDH1A1ASAH1GAAHTT |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-3784571-A | ORGANIC ACID ADDITION SALTS OF 1-(BUTYL-CARBAMOYL) - 2-(METHYLAMINO)-BENZIMIDAZOLE AND METHOD FOR PREPARING THE SAME | DODDS D | 1974-01-08 | — | — | US | disclosed |