Predicted protein targets (top 10)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ASAH1 | Q13510 | 9/20 | 0.73 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.67 |
| ▸ | TSHR | P16473 | 1/20 | 0.67 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.52 |
| ▸ | GAA | P10253 | 1/20 | 0.48 |
| ▸ | HTT | P42858 | 1/20 | 0.48 |
| ▸ | BCHE | P06276 | 1/20 | 0.48 |
| ▸ | LMNA | P02545 | 1/20 | 0.47 |
| ▸ | TP53 | P04637 | 1/20 | 0.47 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.46 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| Carbamic Acid SCHEMBL3114700 | 0.95 | ASAH1 (0.71) | ASAH1ALDH1A1TSHRKMT2AGAA | |
| SCHEMBL11743315 | 0.85 | ASAH1 (0.90) | ASAH1ALDH1A1TSHRKMT2ALMNA | |
| SCHEMBL6926893 | 0.85 | TSHR (0.79) | ASAH1ALDH1A1TSHRKMT2AGAA | |
| SCHEMBL11884864 | 0.84 | TSHR (0.74) | ASAH1ALDH1A1TSHRKMT2AGAA | |
| SCHEMBL27523135 | 0.84 | ASAH1 (0.65) | ASAH1ALDH1A1TSHRGAAHTT | |
| SCHEMBL22798839 | 0.84 | ASAH1 (0.61) | ASAH1ALDH1A1TSHRKMT2AGAA | |
| SCHEMBL29795669 | 0.83 | ASAH1 (0.84) | ASAH1ALDH1A1TSHRKMT2AGAA | |
| SCHEMBL28794572 | 0.83 | ASAH1 (0.84) | ASAH1ALDH1A1TSHRKMT2AGAA | |
| SCHEMBL29795738 | 0.82 | ALDH1A1 (0.65) | ASAH1ALDH1A1TSHRGAAHTT | |
| SCHEMBL28794826 | 0.82 | ALDH1A1 (0.65) | ASAH1ALDH1A1TSHRGAAHTT |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1736471-B1 | 3-(DIHYDRO(TETRAHYDRO)ISOQUINOLIN-1-YL)QUINOLINES | MITSUI CHEMICALS AGRO INC (JP) | 2014-01-08 | — | — | EP | claimed |
| US-6465498-B2 | STABLE MICROBICIDAL FORMULATION, SOLUBILITY IN LIQUID PREPARATIONS | AIR LIQUIDE SANTE (INTERNATIONAL) (FR) | 2002-10-15 | — | — | US | claimed |
| EP-0173668-B2 | RECOMBINANT SACCHAROMYCES | SMITHKLINE BEECHAM CORPORATION (US) | 1992-07-15 | — | — | EP | disclosed |
| US-4303668-A | DEHYDROACETIC ACID AND TETRACHLOROISOPHTHALONITRILE | NIPPON GOHSEI KAGAKU KOGYO KABUSHIKI KAISHA (JP) | 1981-12-01 | — | — | US | disclosed |