SCHEMBL11889708

SCHEMBL11889708

CCCCC[C@H](CN(O)C=O)C(=O)NCNC(=O)Oc1ccc(C(F)(F)F)o1

nearest known ligand 0.54

Predicted protein targets (top 4)

geneUniProtsupporting neighboursconfidence
BMP1 P13497 10/20 0.54
MMP12 P39900 4/20 0.51
TLL1 O43897 1/20 0.38
TLL2 Q9Y6L7 1/20 0.38

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL11889625 0.80 BMP1 (0.59) BMP1MMP12TLL1TLL2
SCHEMBL11889413 0.77 BMP1 (0.52) BMP1MMP12TLL1TLL2
SCHEMBL11889610 0.77 BMP1 (0.61) BMP1MMP12TLL1TLL2
SCHEMBL11890162 0.77 BMP1 (0.54) BMP1MMP12TLL1TLL2
SCHEMBL11889580 0.76 BMP1 (0.78) BMP1MMP12TLL1TLL2
SCHEMBL11889727 0.76 BMP1 (0.57) BMP1MMP12TLL1TLL2
SCHEMBL11889688 0.75 BMP1 (0.52) BMP1MMP12TLL1TLL2
SCHEMBL11889444 0.74 BMP1 (0.47) BMP1MMP12TLL1TLL2
SCHEMBL11889592 0.72 BMP1 (0.52) BMP1MMP12
SCHEMBL11889369 0.72 BMP1 (0.58) BMP1MMP12

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-1585757-B1 PEPTIDE DEFORMYLASE INHIBITORS GLAXOSMITHKLINE LLC (US) 2012-08-01 EP claimed