SCHEMBL118900

SCHEMBL118900

Nc1ccc2cccnc2c1

nearest known ligand 0.70

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
ALDH1A1 P00352 6/20 0.70
HTT P42858 4/20 0.70
CASP1 P29466 3/20 0.70
MAPT P10636 3/20 0.70
HSD17B10 Q99714 3/20 0.70
ATM Q13315 2/20 0.70
KDM4E B2RXH2 2/20 0.70
TP53 P04637 2/20 0.70
HSP90AA1 P07900 2/20 0.70
TSHR P16473 2/20 0.70
SMN1; SMN2 Q16637 2/20 0.70
HSP90AB1 P08238 1/20 0.70
MEN1 O00255 3/20 0.59
KMT2A Q03164 3/20 0.59
CASP7 P55210 2/20 0.59
CYP1A2 P05177 1/20 0.59
CYP2C19 P33261 1/20 0.59
NR4A2 P43354 1/20 0.59
HTR3A P46098 1/20 0.53
CASP6 P55212 1/20 0.53

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL30045789 1.00 ALDH1A1 (0.70) ALDH1A1HTTCASP1MAPTHSD17B10
Hydrochloric Acid SCHEMBL2814587 0.98 ALDH1A1 (0.68) ALDH1A1HTTCASP1MAPTHSD17B10
SCHEMBL7197718 0.98 ALDH1A1 (0.68) ALDH1A1HTTCASP1MAPTHSD17B10
Hydrochloric Acid SCHEMBL4263418 0.98 ALDH1A1 (0.68) ALDH1A1HTTCASP1MAPTHSD17B10
Hydrochloric Acid SCHEMBL29933605 0.98 ALDH1A1 (0.68) ALDH1A1HTTCASP1MAPTHSD17B10
Ethane SCHEMBL27910145 0.96 ALDH1A1 (0.66) ALDH1A1HTTCASP1MAPTHSD17B10
Quinoline SCHEMBL28837832 0.94 ALDH1A1 (0.69) ALDH1A1HTTCASP1MAPTHSD17B10
Formaldehyde SCHEMBL28757678 0.94 ALDH1A1 (0.63) ALDH1A1HTTCASP1MAPTHSD17B10
Formic Acid SCHEMBL30945585 0.89 ALDH1A1 (0.58) ALDH1A1HTTCASP1MAPTHSD17B10
SCHEMBL28084480 0.84 ALDH1A1 (0.56) ALDH1A1HTTCASP1MAPTHSD17B10

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 811 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
CN-119775997-A Quinoline modified nano white carbon black zinc ion fluorescent probe based on surface imprinting technology and application thereof 江苏海洋大学 2025-04-08 CN claimed
CN-119285947-A Low-temperature curing polyimide precursor solution and preparation method thereof 北京化工大学常州先进材料研究院 2025-01-10 CN claimed
CN-117510879-B UIO-66 (Zr) metal organic framework fluorescent probe for zinc ion detection and preparation method thereof 江苏海洋大学 2024-09-24 CN claimed
CN-117510879-A UIO-66 (Zr) metal organic framework fluorescent probe for zinc ion detection and preparation method thereof 江苏海洋大学 2024-02-06 CN claimed
EP-4044211-A1 MALDI-MS METHOD, PHOTO-SENSITIVE MALDI MATRIX COMPOSITE AND PHOTO-CAGED MALDI MATRIX COMPOUND FOR USE IN SAID METHOD AND RESPECTIVE USES Sirius Fine Chemicals SiChem GmbH (DE) 2022-08-17 EP claimed
CN-110194760-B Process for preparing 3-benzylidene-2- (7' -quinoline) -2, 3-dihydro-isoindol-1-ones 浙江农林大学暨阳学院 2021-08-17 CN claimed
CN-109265783-B Aging-resistant transformer oil conservator diaphragm 国网江苏省电力公司盐城供电公司 2020-08-28 CN claimed
CN-110669058-A Tricyclic quinolone carboxylic acid and preparation method thereof 江西农业大学 2020-01-10 CN claimed
CN-105530938-B Compounds for the treatment of diseases caused by retroviruses ABIVAX公司 2019-10-22 CN claimed
CN-110194760-A Prepare 3- benzal -2-(7 '-quinoline) methods of -2,3- dihydro-isoindole -1- ketone compounds 浙江农林大学暨阳学院 2019-09-03 CN claimed
CN-109265783-A A kind of ageing-resistant transformer oil storage diaphragm 国网江苏省电力公司盐城供电公司 2019-01-25 CN claimed
CN-109020885-A Aminoquinolines and its preparation method and application 中国人民解放军成都军区总医院 2018-12-18 CN claimed
CN-104945379-B Compounds for the treatment of premature aging and especially premature aging ABIVAX公司 2018-11-30 CN claimed
CN-105530938-A Compounds for the treatment of diseases caused by retroviruses ABIVAX 2016-04-27 CN claimed
EP-2970215-A1 PYRROLIDINE DERIVATIVES, PHARMACEUTICAL COMPOSITIONS CONTAINING THEM, AND THEIR USE IN THERAPY AbbVie Deutschland GmbH & Co. KG (DE) 2016-01-20 EP claimed
CN-104945378-A Compounds for the treatment of premature aging and especially premature aging ABIVAX 2015-09-30 CN claimed
CN-104945379-A Compounds for the treatment of premature aging and especially premature aging ABIVAX 2015-09-30 CN claimed
WO-2014140310-A1 PYRROLIDINE DERIVATIVES, PHARMACEUTICAL COMPOSITIONS CONTAINING THEM, AND THEIR USE IN THERAPY AbbVie Deutschland GmbH & Co. KG (DE) 2014-09-18 WO claimed
EP-2074089-B1 ORGANIC COMPOUNDS NOVARTIS AG (CH) 2013-09-18 EP claimed
EP-0785190-B1 Quinolinone derivative and antiallergic agent with said quinolinone derivative as the active ingredient DAINIPPON INK & CHEMICALS (JP) 2000-08-16 EP claimed