Predicted protein targets (top 11)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HSD17B10 | Q99714 | 2/20 | 0.36 |
| ▸ | LMNA | P02545 | 2/20 | 0.36 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.36 |
| ▸ | RIPK1 | Q13546 | 1/20 | 0.35 |
| ▸ | DPP4 | P27487 | 5/20 | 0.34 |
| ▸ | PREP | P48147 | 2/20 | 0.33 |
| ▸ | DPP8 | Q6V1X1 | 3/20 | 0.32 |
| ▸ | DPP9 | Q86TI2 | 3/20 | 0.32 |
| ▸ | FAP | Q12884 | 2/20 | 0.32 |
| ▸ | DPP7 | Q9UHL4 | 2/20 | 0.32 |
| ▸ | PKM | P14618 | 1/20 | 0.31 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL14480015 | 0.77 | DPP4 (0.40) | HSD17B10LMNACYP2C19RIPK1DPP4 | |
| SCHEMBL26697063 | 0.77 | HSD17B10 (0.39) | HSD17B10LMNACYP2C19RIPK1DPP4 | |
| SCHEMBL13860171 | 0.77 | HSD17B10 (0.38) | HSD17B10LMNACYP2C19RIPK1DPP4 | |
| SCHEMBL1920132 | 0.77 | DPP4 (0.40) | HSD17B10LMNACYP2C19RIPK1DPP4 | |
| SCHEMBL2591304 | 0.77 | HSD17B10 (0.38) | HSD17B10LMNACYP2C19RIPK1DPP4 | |
| SCHEMBL5002190 | 0.77 | DPP4 (0.40) | HSD17B10LMNACYP2C19RIPK1DPP4 | |
| SCHEMBL4388287 | 0.77 | HSD17B10 (0.38) | HSD17B10LMNACYP2C19RIPK1DPP4 | |
| SCHEMBL4390283 | 0.77 | HSD17B10 (0.38) | HSD17B10LMNACYP2C19RIPK1DPP4 | |
| SCHEMBL2430899 | 0.77 | DPP4 (0.40) | HSD17B10LMNACYP2C19RIPK1DPP4 | |
| SCHEMBL28409987 | 0.76 | HSD17B10 (0.37) | HSD17B10LMNACYP2C19RIPK1DPP4 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-7893056-B2 | Peptide deformylase inhibitors | GLAXOSMITHKLINE LLC (US) | 2011-02-22 | — | — | US | disclosed |